Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.43 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | MPO | P05164 | 3/20 | 0.39 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30898252 | 0.88 | CYP4F2 (0.48) | TYRNPC1RAB9AMAPTTSHR | |
| SCHEMBL27571702 | 0.84 | IDO1 (0.44) | AKR1B1ANO1MAPTADRB2ADRB1 | |
| SCHEMBL28288433 | 0.84 | ALDH1A1 (0.39) | TYRNPC1RAB9AMAPTTSHR | |
| SCHEMBL27812449 | 0.84 | F2 (0.37) | TYRNPC1RAB9AMAPTTSHR | |
| SCHEMBL27741038 | 0.84 | ALDH1A1 (0.48) | TAAR1ANO1NPC1RAB9AMAPT | |
| SCHEMBL27796948 | 0.84 | RIPK1 (0.43) | TAAR1ANO1NPC1RAB9AMAPT | |
| SCHEMBL12251059 | 0.81 | MTNR1A (0.48) | — | |
| SCHEMBL23630606 | 0.80 | NPC1 (0.55) | AKR1B1AKR1B10NPC1RAB9AMAPT | |
| SCHEMBL30898281 | 0.79 | CYP4F2 (0.49) | AKR1B1AKR1B10NPC1RAB9AMAPT | |
| SCHEMBL28165196 | 0.78 | KDM4E (0.38) | RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107074887-A | Substituted-dihydro pyrrolo-pyrazole compound | 宇部兴产株式会社 | 2017-08-18 | — | — | CN | disclosed |