SCHEMBL30898281

SCHEMBL30898281

CC(C)(C)NC(=O)OCCCc1ccccc1CO

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 2/20 0.49
CYP4A11 Q02928 2/20 0.49
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
RECQL P46063 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
MAPT P10636 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
POLB P06746 1/20 0.36
PSEN1 P49768 1/20 0.36
PSEN2 P49810 1/20 0.36
APH1B Q8WW43 1/20 0.36
NCSTN Q92542 1/20 0.36
APH1A Q96BI3 1/20 0.36
PSENEN Q9NZ42 1/20 0.36
CTSK P43235 1/20 0.36
NAAA Q02083 3/20 0.36
LMNA P02545 1/20 0.36
CHRNA7 P36544 1/20 0.35
AKR1B10 O60218 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30898252 0.91 CYP4F2 (0.48) CYP4F2CYP4A11NPC1RAB9ARECQL
SCHEMBL28263155 0.84 RIPK1 (0.42) NPC1RAB9ARECQLSMN1; SMN2MAPT
SCHEMBL27611273 0.81 NPC1 (0.63) NPC1RAB9ARECQLSMN1; SMN2MAPT
SCHEMBL28848147 0.79 TYR (0.51) NPC1RAB9AMAPTAKR1B10AKR1B1
SCHEMBL27812449 0.78 F2 (0.37) CYP4F2CYP4A11NPC1RAB9ASMN1; SMN2
SCHEMBL30898286 0.78 NPC1 (0.46) CYP4F2CYP4A11NPC1RAB9ARECQL
SCHEMBL29278320 0.77 NPC1 (0.57) NPC1RAB9ARECQLSMN1; SMN2MAPT
SCHEMBL12251059 0.76 MTNR1A (0.48) TDP1
SCHEMBL27796948 0.75 RIPK1 (0.43) NPC1RAB9AMAPTPOLBCTSK
SCHEMBL27741038 0.75 ALDH1A1 (0.48) NPC1RAB9ASMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024105159-A1 LIGANDS OF THE M6A-RNA READERS UNIVERSITY OF ZURICH (CH) 2024-05-23 WO disclosed