Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 4/20 | 0.41 |
| ▸ | CDK9 | P50750 | 4/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.35 |
| ▸ | NEK2 | P51955 | 1/20 | 0.34 |
| ▸ | CREB1 | P16220 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29195639 | 0.89 | CDK2 (0.41) | CDK2CDK9METBCHEACHE | |
| SCHEMBL28848489 | 0.84 | CDK9 (0.55) | CDK2CDK9METBCHEACHE | |
| SCHEMBL28848493 | 0.84 | CDK2 (0.42) | CDK2CDK9METBCHEACHE | |
| SCHEMBL28848503 | 0.83 | BCHE (0.48) | BCHEACHECYP1A1CYP1A2CYP1B1 | |
| SCHEMBL29876405 | 0.76 | MAPT (0.54) | BCHEACHEL3MBTL1CREB1PPARG | |
| SCHEMBL28848479 | 0.73 | PARP1 (0.52) | CDK2CDK9METBCHEACHE | |
| SCHEMBL29195640 | 0.72 | BCHE (0.47) | BCHEACHECYP1A1CYP1A2CYP1B1 | |
| SCHEMBL28848486 | 0.71 | CDK9 (0.51) | CDK2CDK9METBCHEACHE | |
| SCHEMBL28848659 | 0.68 | ACHE (0.67) | CDK2CDK9METBCHEACHE | |
| SCHEMBL28848526 | 0.64 | ACHE (0.60) | CDK2CDK9BCHEACHECCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114957182-A | USP8 inhibitor containing flavone skeleton structure and application thereof | 中国药科大学 | 2022-08-30 | — | — | CN | disclosed |