Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 4/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 3/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30949892 | 0.82 | HTR2A (0.59) | HTR2AHTR2CHTR2B | |
| SCHEMBL22946219 | 0.79 | PTGS2 (0.55) | CNR2HTR2ACA2CNR1SIGMAR1 | |
| SCHEMBL28848580 | 0.79 | HTR1A (0.39) | HTR2AHTR2CCA1CA2CA9 | |
| SCHEMBL26684636 | 0.79 | CNR2 (0.45) | CNR2HTR2AHTR2CCA1CA2 | |
| SCHEMBL26684590 | 0.77 | CNR2 (0.46) | CNR2HTR2ACA1CA2CNR1 | |
| SCHEMBL5833688 | 0.75 | HTR2A (0.64) | TNKS2HTR2AHTR2CHTR2BCA1 | |
| SCHEMBL15240817 | 0.75 | TNKS2 (0.67) | TNKS2HTR2AHTR2CHTR2BCA1 | |
| SCHEMBL2445118 | 0.73 | TNKS2 (0.50) | TNKS2HTR2AHTR2CHTR2BAKR1B1 | |
| SCHEMBL30038814 | 0.73 | HTR2A (0.44) | CNR2HTR2AHTR2CCA1CA2 | |
| SCHEMBL17087121 | 0.72 | ACHE (0.50) | ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114957171-B | Novel five-membered heterocycle substituted styrene derivative and preparation method and application thereof | 广东工业大学 | 2024-07-30 | — | — | CN | disclosed |
| CN-114957171-A | Novel five-membered heterocyclic substituted styrene derivative and preparation method and application thereof | 广东工业大学 | 2022-08-30 | — | — | CN | disclosed |