Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 6/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | PRKDC | P78527 | 1/20 | 0.35 |
| ▸ | ATR | Q13535 | 1/20 | 0.35 |
| ▸ | COMT | P21964 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | GPR3 | P46089 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17891982 | 0.87 | MAPT (0.38) | MAPTTP53SMN1; SMN2THRBTRPM8 | |
| SCHEMBL24726391 | 0.78 | MAOA (0.34) | MAPTTP53SMN1; SMN2THRBTRPM8 | |
| SCHEMBL28167999 | 0.74 | KMT2A (0.39) | NPC1MAOATDP1KDM4EGPR3 | |
| SCHEMBL24725971 | 0.72 | GAA (0.46) | NPC1RAB9A | |
| SCHEMBL3297650 | 0.69 | CNR2 (0.52) | MAPTTP53NPC1TDP1KDM4E | |
| SCHEMBL15782859 | 0.67 | NPC1 (0.43) | MAPTTRPM8NPC1MAOATDP1 | |
| SCHEMBL28167955 | 0.67 | ALDH1A1 (0.42) | MAPTSMN1; SMN2NPC1KDM4EKMT2A | |
| SCHEMBL11137432 | 0.66 | KMT2A (0.43) | MAPTTP53TDP1KDM4EKMT2A | |
| SCHEMBL28592395 | 0.65 | COMT (0.41) | MAPTCOMTTDP1KDM4EL3MBTL1 | |
| SCHEMBL8882478 | 0.65 | FDPS (0.43) | MAPTTP53SMN1; SMN2NPC1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107108612-A | The active tetracyclic of harmful organism is killed with sulfur-bearing substituent | 先正达参股股份有限公司 | 2017-08-29 | — | — | CN | disclosed |