Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
| ▸ | SDHB | P21912 | 1/20 | 0.43 |
| ▸ | MDH1 | P40925 | 1/20 | 0.42 |
| ▸ | MDH2 | P40926 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21036244 | 0.81 | CA1 (0.47) | PDK2RAB9APOLBALDH1A1LOXL2 | |
| SCHEMBL28168249 | 0.81 | KDM4C (0.46) | PDK2ALDH1A1HPGD | |
| SCHEMBL12985400 | 0.79 | PDK2 (0.46) | PDK2RAB9APOLBALDH1A1LOXL2 | |
| SCHEMBL24852732 | 0.79 | NOTUM (0.40) | PDK2RAB9APOLBALDH1A1NPC1 | |
| SCHEMBL29918286 | 0.79 | NOTUM (0.40) | PDK2RAB9APOLBALDH1A1NPC1 | |
| SCHEMBL3942652 | 0.78 | LOXL2 (0.49) | RAB9APOLBALDH1A1LOXL2NPC1 | |
| SCHEMBL21609774 | 0.78 | NOTUM (0.56) | PDK2POLBNOTUM | |
| SCHEMBL17709905 | 0.78 | NOTUM (0.56) | PDK2POLBALDH1A1MAPTEPHX2 | |
| SCHEMBL21296558 | 0.77 | SIGMAR1 (0.37) | ALDH1A1TSHRMAPTEPHX2OPRM1 | |
| SCHEMBL1670244 | 0.77 | LOXL2 (0.51) | RAB9APOLBALDH1A1LOXL2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107108598-A | Thiazoles as Ror gamma t modulators | 詹森药业有限公司 | 2017-08-29 | — | — | CN | disclosed |