Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24852732 | 1.00 | NOTUM (0.40) | NOTUMMEN1KMT2ALMNACA12 | |
| SCHEMBL21609774 | 0.84 | NOTUM (0.56) | NOTUMLMNACA12CA1CA2 | |
| SCHEMBL17709905 | 0.84 | NOTUM (0.56) | NOTUMMEN1KMT2ALMNACA12 | |
| SCHEMBL24852726 | 0.81 | HCAR1 (0.46) | L3MBTL1PDK2EPHX2NR1H4 | |
| SCHEMBL24526586 | 0.80 | CA12 (0.42) | NOTUMMEN1KMT2ALMNACA12 | |
| SCHEMBL28849065 | 0.79 | PDK2 (0.49) | NOTUMPOLBPDK2MAPTNPC1 | |
| SCHEMBL31237048 | 0.79 | CA12 (0.41) | NOTUMMEN1KMT2ALMNACA12 | |
| SCHEMBL21036244 | 0.78 | CA1 (0.47) | NOTUMMEN1KMT2ACA12CA1 | |
| SCHEMBL24526955 | 0.78 | PKM (0.42) | NOTUMMEN1KMT2ALMNACA12 | |
| SCHEMBL29759156 | 0.78 | PKM (0.42) | NOTUMMEN1KMT2ALMNACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4055016-A1 | GPR52 MODULATOR COMPOUNDS | Heptares Therapeutics Limited (GB) | 2022-09-14 | — | — | EP | disclosed |