SCHEMBL28849342

SCHEMBL28849342

Cc1ccc(P(=O)(O)O)c(P(=O)(O)O)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.44
LMNA P02545 1/20 0.44
CYP1A2 P05177 3/20 0.41
CYP2D6 P10635 1/20 0.41
PTK2B Q14289 1/20 0.40
RXFP1 Q9HBX9 1/20 0.40
TRPA1 O75762 1/20 0.37
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
MMP8 P22894 1/20 0.36
ACP3 P15309 1/20 0.36
CYP2A6 P11509 2/20 0.36
TP53 P04637 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
HPGD P15428 1/20 0.36
PGK1 P00558 2/20 0.35
PGK2 P07205 2/20 0.35
GAA P10253 1/20 0.35
CSNK2A1 P68400 1/20 0.34
FDPS P14324 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL563887 0.84 CYP1A2 (0.51) TSHRLMNACYP1A2CYP2D6PTK2B
SCHEMBL3353304 0.84 LMNA (0.43) TSHRLMNACYP1A2CYP2D6PTK2B
SCHEMBL30155025 0.84 CYP1A2 (0.51) TSHRLMNACYP1A2CYP2D6PTK2B
SCHEMBL27444175 0.82 TRPA1 (0.50) TSHRLMNAPTK2BRXFP1TRPA1
Hydrochloric Acid SCHEMBL10914729 0.82 CYP1A2 (0.50) TSHRLMNACYP1A2CYP2D6PTK2B
SCHEMBL17607326 0.80 ALOX15 (0.48) TSHRLMNACYP1A2CYP2D6PTK2B
SCHEMBL29633722 0.80 ALOX15 (0.48) TSHRLMNACYP1A2CYP2D6PTK2B
SCHEMBL7823987 0.80 PTPN1 (0.41) TSHRLMNACYP1A2CYP2D6PTK2B
SCHEMBL3395636 0.79 LMNA (0.39) TSHRLMNACYP1A2CYP2D6PTK2B
SCHEMBL13978729 0.77 ACHE (0.52) TSHRCYP1A2TP53GAACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107075097-A Catalyst composition for polyester production process 科莱恩塑料和涂料有限公司 2017-08-18 CN disclosed