Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30915390 | 0.82 | LMNA (0.35) | NPSR1OPRM1SLC6A2SLC6A4CYP4F2 | |
| SCHEMBL24680602 | 0.79 | NPSR1 (0.42) | NPSR1CYP4F2CYP4A11LMNA | |
| SCHEMBL6222739 | 0.76 | OPRK1 (0.46) | OPRM1OPRK1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL12462298 | 0.73 | NPSR1 (0.46) | NPSR1CYP4F2CYP4A11LMNA | |
| SCHEMBL225044 | 0.73 | NPSR1 (0.46) | NPSR1CYP4F2CYP4A11LMNA | |
| SCHEMBL30149681 | 0.72 | NPSR1 (0.44) | NPSR1CYP4F2CYP4A11LMNA | |
| SCHEMBL25718014 | 0.72 | SLC6A2 (0.33) | OPRM1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL15125183 | 0.71 | NPSR1 (0.38) | NPSR1OPRM1OPRK1CYP4F2CYP4A11 | |
| SCHEMBL31733084 | 0.71 | NPSR1 (0.38) | NPSR1CYP4F2CYP4A11LMNA | |
| SCHEMBL7370344 | 0.69 | CYP4F2 (0.36) | OPRM1OPRK1SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022199586-A1 | PYRIMIDOPYRIDINE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | 苏州泽璟生物制药股份有限公司 | 2022-09-29 | — | — | WO | disclosed |
| CN-115109078-A | Pyrimidopyridine inhibitor and preparation method and application thereof | 苏州泽璟生物制药股份有限公司 | 2022-09-27 | — | — | CN | disclosed |