Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 2/20 | 0.60 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.60 |
| ▸ | PTPRC | P08575 | 1/20 | 0.60 |
| ▸ | SCN8A | Q9UQD0 | 13/20 | 0.58 |
| ▸ | SCN10A | Q9Y5Y9 | 13/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.58 |
| ▸ | JAK2 | O60674 | 1/20 | 0.56 |
| ▸ | JAK1 | P23458 | 1/20 | 0.56 |
| ▸ | TYK2 | P29597 | 1/20 | 0.56 |
| ▸ | F2R | P25116 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17045005 | 0.82 | SCN8A (0.65) | PTPRCSCN8ASCN10AJAK2JAK1 | |
| SCHEMBL23027376 | 0.79 | JAK2 (0.56) | SCN8ASCN10AJAK2JAK1TYK2 | |
| SCHEMBL5332281 | 0.78 | KCNK3 (0.75) | KCNK3KCNK9PTGS1PTPRCRXFP1 | |
| SCHEMBL15901652 | 0.76 | SCN10A (0.69) | SCN8ASCN10A | |
| SCHEMBL15901646 | 0.76 | SCN10A (0.72) | SCN8ASCN10A | |
| SCHEMBL28822369 | 0.76 | ESR1 (0.65) | SCN8ASCN10A | |
| Bromide SCHEMBL16777889 | 0.75 | SCN10A (0.68) | SCN8ASCN10A | |
| SCHEMBL28064012 | 0.75 | SCN8A (0.67) | SCN8ASCN10A | |
| SCHEMBL15901904 | 0.75 | NPC1 (0.61) | KCNK3KCNK9SCN8ASCN10AJAK2 | |
| SCHEMBL12764065 | 0.75 | KCNK3 (0.83) | KCNK3KCNK9PTGS1PTPRCRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114945566-A | Substituted tetrahydrofurans as sodium channel modulators | 沃泰克斯药物股份有限公司 | 2022-08-26 | — | — | CN | disclosed |