Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 12/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 2/20 | 0.47 |
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28850336 | 0.90 | FAAH (0.51) | FAAHPOLBCNR1CNR2CYP2C19 | |
| SCHEMBL20898384 | 0.86 | NOS2 (0.51) | FAAHPOLBCNR1CNR2CYP2C19 | |
| SCHEMBL20900383 | 0.86 | NOS2 (0.51) | FAAHPOLBCNR1CNR2CYP2C19 | |
| SCHEMBL29631806 | 0.86 | NOS2 (0.51) | FAAHPOLBCNR1CNR2CYP2C19 | |
| SCHEMBL9356782 | 0.86 | MEN1 (0.56) | KCNH2MGLLLMNACHRM2SLC6A2 | |
| SCHEMBL28093862 | 0.86 | GPR119 (0.51) | FAAHPOLBCNR1KCNH2LMNA | |
| SCHEMBL28093861 | 0.86 | GPR119 (0.51) | FAAHPOLBCNR1KCNH2LMNA | |
| SCHEMBL9533373 | 0.84 | BCHE (0.52) | FAAHPOLB | |
| SCHEMBL14198313 | 0.84 | CYP2D6 (0.57) | FAAHCYP2C19KCNH2LMNACHRM2 | |
| SCHEMBL18620485 | 0.83 | FAAH (0.44) | FAAHCNR1CNR2CYP2C19KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114805302-A | Preparation method of 4- [ (4-chlorphenyl) -2-pyridylmethoxy ] -1-piperidine carboxylate | 北京联本医药化学技术有限公司 | 2022-07-29 | — | — | CN | claimed |
| CN-114805302-B | Preparation method of 4- [ (4-chlorophenyl) -2-pyridylmethoxy ] -1-piperidine carboxylic ester | 北京联本医药化学技术有限公司 | 2024-04-12 | — | — | CN | disclosed |
| CN-114805302-B | Preparation method of 4- [ (4-chlorophenyl) -2-pyridylmethoxy ] -1-piperidine carboxylic ester | 北京联本医药化学技术有限公司 | 2024-04-12 | — | — | CN | disclosed |
| CN-114805302-A | Preparation method of 4- [ (4-chlorphenyl) -2-pyridylmethoxy ] -1-piperidine carboxylate | 北京联本医药化学技术有限公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-114805302-A | Preparation method of 4- [ (4-chlorphenyl) -2-pyridylmethoxy ] -1-piperidine carboxylate | 北京联本医药化学技术有限公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-114805302-A | Preparation method of 4- [ (4-chlorphenyl) -2-pyridylmethoxy ] -1-piperidine carboxylate | 北京联本医药化学技术有限公司 | 2022-07-29 | — | — | CN | disclosed |