Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.43 |
| ▸ | USP7 | Q93009 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | AKT2 | P31751 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28851911 | 0.88 | KDM4E (0.52) | ALDH1A1POLBGAAMAPTTP53 | |
| SCHEMBL28851913 | 0.85 | ALDH1A1 (0.58) | ALDH1A1POLBGAAMAPTTP53 | |
| SCHEMBL6495192 | 0.85 | SMN1; SMN2 (0.58) | ALDH1A1POLBGAAMAPTTP53 | |
| SCHEMBL28851915 | 0.83 | RAB9A (0.48) | ALDH1A1POLBGAAMAPTTP53 | |
| SCHEMBL28851936 | 0.83 | GAA (0.54) | ALDH1A1POLBGAAMAPTALOX5 | |
| SCHEMBL15825411 | 0.77 | ALDH1A1 (0.62) | ALDH1A1GAAMAPTTP53KDM4E | |
| SCHEMBL3521737 | 0.75 | TUBB4A (0.53) | ALDH1A1GAAMAPTTP53ALOX5 | |
| SCHEMBL28851916 | 0.74 | NR1H4 (0.47) | ALDH1A1GAAMAPTTP53ALOX5 | |
| SCHEMBL19723753 | 0.73 | NR1H4 (0.72) | ALDH1A1POLBGAAMAPTTP53 | |
| SCHEMBL2992153 | 0.73 | ALOX5 (0.84) | ALDH1A1GAAMAPTTP53ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114989167-B | 3,6-dibromo or 3-bromoimidazo [1,2-a ] pyridine derivative and synthesis method thereof | 江苏师范大学 | 2023-08-22 | — | — | CN | disclosed |
| CN-114989167-A | 3,6-dibromo or 3-bromo imidazo [1,2-a ] pyridine derivative and synthesis method thereof | 江苏师范大学 | 2022-09-02 | — | — | CN | disclosed |