Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | SDHB | P21912 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29113152 | 0.80 | TUBB4A (0.43) | SDHBALDH1A1KDM4EPOLBCYP1A2 | |
| SCHEMBL17623925 | 0.78 | HTT (0.46) | MEN1KMT2AALDH1A1KDM4EPOLB | |
| SCHEMBL30636497 | 0.78 | ALDH1A1 (0.56) | SDHBALDH1A1SMN1; SMN2KDM4EPOLB | |
| SCHEMBL28853408 | 0.78 | ALDH1A1 (0.56) | SDHBALDH1A1SMN1; SMN2KDM4EPOLB | |
| SCHEMBL17623924 | 0.73 | BLM (0.58) | MEN1KMT2ASDHBALDH1A1KDM4E | |
| SCHEMBL16302025 | 0.72 | SCN8A (0.53) | TDP1 | |
| SCHEMBL2441955 | 0.72 | SLC6A3 (0.65) | MEN1KMT2AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL10338670 | 0.71 | KMT2A (0.73) | MEN1KMT2AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL4318924 | 0.71 | ALDH1A1 (0.69) | MEN1KMT2AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL9024615 | 0.71 | BDKRB1 (0.52) | SDHBSLC6A3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115124475-A | Pyrimidine derivative and preparation method and application thereof | 贵阳学院 | 2022-09-30 | — | — | CN | claimed |
| CN-115124475-A | Pyrimidine derivative and preparation method and application thereof | 贵阳学院 | 2022-09-30 | — | — | CN | disclosed |