Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 10/20 | 0.52 |
| ▸ | SDHB | P21912 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9024448 | 0.90 | AGTR2 (0.52) | BDKRB1PTGS2 | |
| SCHEMBL9024454 | 0.83 | PTGS2 (0.49) | PTGS2 | |
| SCHEMBL9024952 | 0.82 | AGTR2 (0.48) | BDKRB1PTGS2 | |
| Water SCHEMBL9023803 | 0.81 | AGTR2 (0.48) | BDKRB1PTGS2 | |
| Water SCHEMBL9023809 | 0.81 | AGTR2 (0.48) | BDKRB1PTGS2 | |
| SCHEMBL9024959 | 0.76 | PTGS2 (0.41) | PTGS2 | |
| SCHEMBL9024837 | 0.73 | AGTR2 (0.60) | BDKRB1PTGS2 | |
| SCHEMBL9389105 | 0.73 | AGTR2 (0.57) | BDKRB1 | |
| SCHEMBL3126366 | 0.73 | SLC6A3 (0.58) | BDKRB1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL23354041 | 0.72 | SLC6A3 (0.64) | BDKRB1SLC6A4SLC6A3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611368-B1 | SUBSTITUTED AMINOPYRIMIDINES AS ANGIOTENSIN II ANTAGONISTS | AMERICAN HOME PROD (US) | 1996-02-07 | — | — | EP | disclosed |
| US-5336677-A | ANTAGONIST OF ANGIOTENSIN II | AMERICAN HOME PRODUCTS CORPORATION (US) | 1994-08-09 | — | — | US | disclosed |