Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5298438 | 0.72 | SCN1A (0.32) | — | |
| SCHEMBL9599274 | 0.72 | — | — | |
| SCHEMBL19385854 | 0.71 | G6PC1 (0.38) | SMN1; SMN2LMNATSHRMAPK1 | |
| SCHEMBL19385855 | 0.71 | G6PC1 (0.38) | SMN1; SMN2LMNATSHRMAPK1 | |
| SCHEMBL19385924 | 0.69 | FABP1 (0.39) | KDM4EL3MBTL1LMNAHRH1SLC6A3 | |
| SCHEMBL3793358 | 0.69 | FABP1 (0.39) | KDM4EL3MBTL1LMNAHRH1SLC6A3 | |
| SCHEMBL9093607 | 0.68 | ALDH1A1 (0.42) | PDPK1TSHR | |
| SCHEMBL2891653 | 0.68 | LMNA (0.36) | LMNATSHRTRPA1 | |
| SCHEMBL2893543 | 0.68 | LMNA (0.36) | L3MBTL1LMNATDP1 | |
| SCHEMBL10926412 | 0.67 | NPC1 (0.44) | KDM4ESMN1; SMN2L3MBTL1LMNASLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8754234-B2 | Chiral 2-(benzylsulfinyl)thiazole derivatives and 2-[(1H-pyrazol-4-ylmethyl)sulfinyl]thiazole derivatives, processes for their preparation and their use as herbicides and plant growth regulators | BAYER CROPSCIENCE AG (DE) | 2014-06-17 | — | — | US | claimed |
| US-20100285958-A1 | Chiral 2-(benzylsulfinyl)Thiazole derivatives and 2-[(1H-pyrazol-4-ylmethyl)sulfinyl]thiazole derivatives, processes for their preparation and their use as herbicides and plant growth regulators | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2010-11-11 | — | — | US | claimed |
| EP-2227458-A2 | 2-(BENZYL- AND 1H-PYRAZOL-4-YLMETHYL)SULFINYL-THIAZOL-DERIVATIVES AS HERBICIDES AND PLANT GROWTH REGULATORS | Bayer CropScience AG (DE) | 2010-09-15 | — | — | EP | claimed |
| WO-2009068170-A2 | 2-(BENZYL- AND 1H-PYRAZOL-4-YLMETHYL)SULFINYL THIAZOLE DERIVATIVES AS HERBICIDES AND PLANT GROWTH REGULATORS | BAYER CROPSCIENCE AG (DE) | 2009-06-04 | — | — | WO | claimed |
| EP-2227458-B1 | Chiral 2-(Benzylsulfinyl)-thiazol derivatives and 2-[(1H-pyrazol-4-ylmethyl)sulfinyl]-thiazol derivatives with S-configuration as herbicide plant growth regulators | BAYER IP GMBH (DE) | 2016-06-22 | — | — | EP | disclosed |
| US-8754234-B2 | Chiral 2-(benzylsulfinyl)thiazole derivatives and 2-[(1H-pyrazol-4-ylmethyl)sulfinyl]thiazole derivatives, processes for their preparation and their use as herbicides and plant growth regulators | BAYER CROPSCIENCE AG (DE) | 2014-06-17 | — | — | US | disclosed |
| US-8754234-B2 | Chiral 2-(benzylsulfinyl)thiazole derivatives and 2-[(1H-pyrazol-4-ylmethyl)sulfinyl]thiazole derivatives, processes for their preparation and their use as herbicides and plant growth regulators | BAYER CROPSCIENCE AG (DE) | 2014-06-17 | — | — | US | disclosed |
| US-8754234-B2 | Chiral 2-(benzylsulfinyl)thiazole derivatives and 2-[(1H-pyrazol-4-ylmethyl)sulfinyl]thiazole derivatives, processes for their preparation and their use as herbicides and plant growth regulators | BAYER CROPSCIENCE AG (DE) | 2014-06-17 | — | — | US | disclosed |
| US-20100285958-A1 | Chiral 2-(benzylsulfinyl)Thiazole derivatives and 2-[(1H-pyrazol-4-ylmethyl)sulfinyl]thiazole derivatives, processes for their preparation and their use as herbicides and plant growth regulators | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2010-11-11 | — | — | US | disclosed |
| US-20100285958-A1 | Chiral 2-(benzylsulfinyl)Thiazole derivatives and 2-[(1H-pyrazol-4-ylmethyl)sulfinyl]thiazole derivatives, processes for their preparation and their use as herbicides and plant growth regulators | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2010-11-11 | — | — | US | disclosed |
| US-20100285958-A1 | Chiral 2-(benzylsulfinyl)Thiazole derivatives and 2-[(1H-pyrazol-4-ylmethyl)sulfinyl]thiazole derivatives, processes for their preparation and their use as herbicides and plant growth regulators | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2010-11-11 | — | — | US | disclosed |
| EP-2227458-A2 | 2-(BENZYL- AND 1H-PYRAZOL-4-YLMETHYL)SULFINYL-THIAZOL-DERIVATIVES AS HERBICIDES AND PLANT GROWTH REGULATORS | Bayer CropScience AG (DE) | 2010-09-15 | — | — | EP | disclosed |
| EP-2227458-A2 | 2-(BENZYL- AND 1H-PYRAZOL-4-YLMETHYL)SULFINYL-THIAZOL-DERIVATIVES AS HERBICIDES AND PLANT GROWTH REGULATORS | Bayer CropScience AG (DE) | 2010-09-15 | — | — | EP | disclosed |
| WO-2009068170-A3 | 2-(BENZYL- AND 1H-PYRAZOL-4-YLMETHYL)SULFINYL THIAZOLE DERIVATIVES AS HERBICIDES AND PLANT GROWTH REGULATORS | BAYER CROPSCIENCE AG (DE) | 2009-09-03 | — | — | WO | disclosed |
| WO-2009068170-A2 | 2-(BENZYL- AND 1H-PYRAZOL-4-YLMETHYL)SULFINYL THIAZOLE DERIVATIVES AS HERBICIDES AND PLANT GROWTH REGULATORS | BAYER CROPSCIENCE AG (DE) | 2009-06-04 | — | — | WO | disclosed |
| WO-2009068170-A2 | 2-(BENZYL- AND 1H-PYRAZOL-4-YLMETHYL)SULFINYL THIAZOLE DERIVATIVES AS HERBICIDES AND PLANT GROWTH REGULATORS | BAYER CROPSCIENCE AG (DE) | 2009-06-04 | — | — | WO | disclosed |
| EP-2065374-A1 | 2-(benzyl- and 1H-pyrazol-4-ylmethyl)sulfinyl-thiazol-derivatives as herbicides and plant growth regulators | Bayer CropScience AG (DE) | 2009-06-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100285958-A1 | Chiral 2-(benzylsulfinyl)Thiazole derivatives and 2-[(1H-pyrazol-4-ylmethyl)sulfinyl]thiazole derivatives, processes for their preparation and their use as herbicides and plant growth regulators | STS, SULT2A1, SLTM | PDPK1 983/4885PLA2G4A 4513/4885KDM4E 1930/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.