Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28854244 | 1.00 | KMT2A (0.47) | KMT2ATSHRHSD17B10ALDH1A1L3MBTL1 | |
| SCHEMBL32681721 | 0.82 | CTSS (0.43) | KMT2ATRPA1ATMCTSKCA1 | |
| SCHEMBL18869910 | 0.80 | ROCK2 (0.53) | — | |
| SCHEMBL15336444 | 0.80 | ROCK2 (0.53) | — | |
| SCHEMBL28200955 | 0.76 | CTSK (0.43) | KMT2ATSHRHSD17B10TRPA1MAPT | |
| SCHEMBL28200954 | 0.76 | CTSK (0.43) | KMT2ATSHRHSD17B10TRPA1MAPT | |
| SCHEMBL21208148 | 0.75 | STK17B (0.40) | KMT2AALDH1A1CA1CA2LMNA | |
| SCHEMBL6947166 | 0.75 | CTSK (0.47) | KMT2ATSHRHSD17B10ALDH1A1L3MBTL1 | |
| SCHEMBL14127863 | 0.75 | KMT2A (0.43) | KMT2ATSHRHSD17B10ALDH1A1L3MBTL1 | |
| SCHEMBL12203593 | 0.74 | CTSK (0.62) | KMT2AHSD17B10ALDH1A1MAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107474050-A | 6,7 dihydro-pyrazolos [1,5 a] pyrazine 4 (5H) assimilation compound | 詹森药业有限公司 | 2017-12-15 | — | — | CN | disclosed |