Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.67 |
| ▸ | RXRA | P19793 | 2/20 | 0.60 |
| ▸ | RXRB | P28702 | 2/20 | 0.60 |
| ▸ | RXRG | P48443 | 2/20 | 0.60 |
| ▸ | LTA4H | P09960 | 1/20 | 0.57 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | PGR | P06401 | 1/20 | 0.54 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.52 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11846870 | 0.86 | BCHE (0.63) | MAOBMAOALMNACYP1A2PTGS1 | |
| SCHEMBL11959143 | 0.84 | MAOB (0.72) | MAOBRXRARXRBRXRGMAOA | |
| SCHEMBL11856925 | 0.84 | LMNA (0.69) | MAOBLTA4HMAOAALOX5LMNA | |
| SCHEMBL10599543 | 0.84 | LMNA (0.69) | MAOBLTA4HMAOAALOX5LMNA | |
| SCHEMBL3301781 | 0.82 | PNMT (0.58) | PGRHIF1A | |
| SCHEMBL27961326 | 0.82 | LTA4H (0.58) | MAOBRXRARXRBRXRGLTA4H | |
| SCHEMBL3823697 | 0.81 | RXRA (0.69) | MAOBRXRARXRBRXRGMAOA | |
| Ammonia Solution, Strong SCHEMBL18010559 | 0.80 | PNMT (0.56) | PGRHIF1A | |
| Methyl Alcohol SCHEMBL9626623 | 0.80 | RXRA (0.68) | MAOBRXRARXRBRXRGMAOA | |
| SCHEMBL1680762 | 0.80 | MAOB (1.00) | MAOBRXRARXRBRXRGMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104513283-B | Glucopyranosyl derivatives and its application in medicine | 广东东阳光药业有限公司 | 2018-01-16 | — | — | CN | disclosed |