Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PREP | P48147 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1838102 | 0.85 | PREP (0.37) | NR1H2ESR2USP2SMN1; SMN2PREP | |
| Hydrochloric Acid SCHEMBL28241841 | 0.84 | PREP (0.36) | NR1H2ESR2USP2SMN1; SMN2PREP | |
| SCHEMBL28856336 | 0.84 | CHRM2 (0.38) | NR1H2ESR2USP2SMN1; SMN2PREP | |
| Pyrrole SCHEMBL28865869 | 0.79 | GPR119 (0.32) | NR1H2USP2SMN1; SMN2PREP | |
| Piperazine SCHEMBL28059508 | 0.79 | PREP (0.33) | NR1H2ESR2USP2SMN1; SMN2PREP | |
| SCHEMBL28222533 | 0.75 | MAPK1 (0.35) | NR1H2ESR2USP2SMN1; SMN2PREP | |
| SCHEMBL28113304 | 0.74 | SIGMAR1 (0.32) | NR1H2 | |
| SCHEMBL28171085 | 0.74 | MAPT (0.39) | — | |
| SCHEMBL28171129 | 0.74 | MAPT (0.39) | — | |
| SCHEMBL28244009 | 0.74 | PARP1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104822267-B | The inhibitor and its application method that hepatitis b virus covalence closed cyclic DNA is formed | 巴鲁克·S·布伦博格研究所 | 2018-01-23 | — | — | CN | disclosed |