Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.32 |
| ▸ | PREP | P48147 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | STS | P08842 | 1/20 | 0.30 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1838102 | 0.89 | PREP (0.37) | GPR119PREPCTSKUSP2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28241841 | 0.88 | PREP (0.36) | GPR119PREPCTSKUSP2SMN1; SMN2 | |
| SCHEMBL28856336 | 0.88 | CHRM2 (0.38) | GPR119PREPCTSKUSP2SMN1; SMN2 | |
| Piperazine SCHEMBL28059508 | 0.85 | PREP (0.33) | PREPMAPK1USP2SMN1; SMN2NR1H2 | |
| SCHEMBL28854569 | 0.79 | NR1H2 (0.34) | PREPUSP2SMN1; SMN2NR1H2 | |
| SCHEMBL28223429 | 0.79 | SIGMAR1 (0.32) | MAPK1CTSKUSP2SMN1; SMN2NR1H2 | |
| SCHEMBL28113304 | 0.78 | SIGMAR1 (0.32) | MAPK1NR1H2 | |
| SCHEMBL30733868 | 0.77 | USP2 (0.33) | PREPUSP2SMN1; SMN2 | |
| SCHEMBL29552182 | 0.77 | PREP (0.34) | PREPNR1H2 | |
| SCHEMBL28222533 | 0.76 | MAPK1 (0.35) | GPR119PREPMAPK1USP2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104870442-B | bicyclic heterocyclic compounds and their therapeutic use | 阿斯特克斯治疗有限公司 | 2018-10-19 | — | — | CN | disclosed |