Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 6/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CCND1 | P24385 | 1/20 | 0.36 |
| ▸ | CCND2 | P30279 | 1/20 | 0.36 |
| ▸ | CCND3 | P30281 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 9/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4133896 | 0.75 | CDK4 (0.37) | HDAC1HDAC6HDAC5CDK4CCND1 | |
| SCHEMBL12065990 | 0.74 | KDM4E (0.47) | CDK4CCND1CCND2CCND3 | |
| SCHEMBL29830402 | 0.72 | HDAC1 (0.44) | HDAC1HDAC6HDAC5CDK4CCND1 | |
| SCHEMBL29403992 | 0.72 | FGFR1 (0.38) | MAPTNR3C1CYP19A1 | |
| SCHEMBL4292183 | 0.72 | MAPT (0.38) | MAPTCYP19A1 | |
| SCHEMBL4128204 | 0.71 | CDK4 (0.34) | HDAC1HDAC6HDAC5CDK4CCND1 | |
| SCHEMBL29783013 | 0.70 | METAP2 (0.33) | — | |
| SCHEMBL8268970 | 0.68 | BRPF1 (0.55) | CDK4CCND1CCND2CCND3MAPT | |
| SCHEMBL30833284 | 0.68 | BRPF1 (0.55) | CDK4CCND1CCND2CCND3MAPT | |
| SCHEMBL12065987 | 0.68 | KDM4E (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4085058-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | Syngenta Crop Protection AG (CH) | 2022-11-09 | — | — | EP | disclosed |
| CN-115023425-A | Pesticidally active heterocyclic derivatives with sulfur-containing substituents | 先正达农作物保护股份公司 | 2022-09-06 | — | — | CN | disclosed |