Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 14/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8268970 | 0.77 | BRPF1 (0.55) | MAPTCYP19A1CDC7CDK2 | |
| SCHEMBL30833284 | 0.77 | BRPF1 (0.55) | MAPTCYP19A1CDC7CDK2 | |
| SCHEMBL28855321 | 0.72 | HDAC1 (0.38) | MAPTCYP19A1 | |
| SCHEMBL1054493 | 0.71 | CA12 (0.57) | MAPTDAO | |
| SCHEMBL4133896 | 0.70 | CDK4 (0.37) | MAPTCYP19A1DAOCDC7CDK2 | |
| SCHEMBL12065990 | 0.69 | KDM4E (0.47) | — | |
| SCHEMBL4128204 | 0.66 | CDK4 (0.34) | MAPTCYP19A1DAORAPGEF4 | |
| SCHEMBL4755903 | 0.65 | DAO (0.43) | DAOCDC7CDK2PDE3BPDE3A | |
| SCHEMBL2614351 | 0.65 | BRPF1 (0.55) | MAPTCDC7CDK2PDE3BPDE3A | |
| SCHEMBL30066887 | 0.65 | BRPF1 (0.55) | MAPTCDC7CDK2PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090281100-A1 | Benzimidazole quinolinones and uses thereof | BARSANTI PAUL A | 2009-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090281100-A1 | Benzimidazole quinolinones and uses thereof | GAA, ALPI, IL4I1 | MAPT 575/4885CYP19A1 868/4885DAO 371/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.