SCHEMBL30833284

SCHEMBL30833284

Cn1c(=O)ccc2ccncc21

nearest known ligand 0.55

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
BRPF1 P55201 3/20 0.55
CA12 O43570 1/20 0.55
BRD4 O60885 1/20 0.55
CA9 Q16790 1/20 0.55
KAT2B Q92831 1/20 0.55
BRD9 Q9H8M2 1/20 0.55
MAPT P10636 12/20 0.43
CYP19A1 P11511 3/20 0.41
CDC7 O00311 1/20 0.39
CDK2 P24941 1/20 0.39
CDK4 P11802 1/20 0.39
CCND1 P24385 1/20 0.39
CCND2 P30279 1/20 0.39
CCND3 P30281 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8268970 1.00 BRPF1 (0.55) BRPF1CA12BRD4CA9KAT2B
SCHEMBL2614351 0.85 BRPF1 (0.55) BRPF1CA12BRD4CA9KAT2B
SCHEMBL30066887 0.85 BRPF1 (0.55) BRPF1CA12BRD4CA9KAT2B
SCHEMBL4292183 0.77 MAPT (0.38) MAPTCYP19A1CDC7CDK2
SCHEMBL35211518 0.76 BRPF1 (0.53) BRPF1CA12BRD4CA9KAT2B
SCHEMBL1356214 0.76 BRPF1 (0.53) BRPF1CA12BRD4CA9KAT2B
SCHEMBL31743104 0.75 HTR6 (0.54) BRPF1CA12BRD4CA9KAT2B
SCHEMBL31743102 0.74 HTR1D (0.54) BRPF1CA12BRD4CA9KAT2B
Pyridine SCHEMBL11505119 0.73 BRPF1 (0.76) BRPF1CA12BRD4CA9KAT2B
SCHEMBL24312103 0.72 HASPIN (0.44) MAPTCYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260124198-A1 ANTIVIRAL PYRAZOLOPYRIDINONE COMPOUNDS GILEAD SCIENCES INC (US) 2026-05-07 US claimed
US-20260124198-A1 ANTIVIRAL PYRAZOLOPYRIDINONE COMPOUNDS GILEAD SCIENCES INC (US) 2026-05-07 US disclosed
CN-119343339-A Heterocyclic GLP-1 agonists 加舒布鲁姆生物公司 2025-01-21 CN disclosed
CN-117580829-A Quinoline and azaquinolines as inhibitors of CD38 勃林格英格翰国际有限公司 2024-02-20 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260124198-A1 ANTIVIRAL PYRAZOLOPYRIDINONE COMPOUNDS ZC3HAV1, CCR1, CCR6 BRPF1 2763/4885CA12 1079/4885BRD4 615/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.