Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NT5E | P21589 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 4/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | SLC13A5 | Q86YT5 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL658697 | 0.81 | LMNA (0.43) | ALDH1A1TSHRLMNANT5ECA2 | |
| SCHEMBL11757972 | 0.78 | TSHR (0.55) | ALDH1A1TSHRKCNJ1KCNH2 | |
| SCHEMBL11392069 | 0.75 | ALDH1A1 (0.40) | ALDH1A1TSHRLMNANT5ECA2 | |
| SCHEMBL10318595 | 0.75 | SPHK2 (0.40) | ALDH1A1TSHRLMNANT5ECA2 | |
| SCHEMBL2723128 | 0.74 | TNNC1 (0.50) | ALDH1A1KCNH2LMNACA2 | |
| SCHEMBL11583429 | 0.74 | LMNA (0.56) | ALDH1A1TSHRKCNH2LMNANT5E | |
| SCHEMBL11118938 | 0.74 | LMNA (0.43) | ALDH1A1TSHRKCNJ1KCNH2LMNA | |
| SCHEMBL778771 | 0.74 | LMNA (0.43) | ALDH1A1TSHRKCNH2LMNANT5E | |
| SCHEMBL4930091 | 0.73 | TSHR (0.61) | ALDH1A1TSHRKCNJ1KCNH2CA2 | |
| SCHEMBL775755 | 0.71 | LMNA (0.41) | ALDH1A1TSHRLMNANT5ECA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105473574-B | Somatostatin receptor subtype 4(SSTR4) agonists | 森特克森治疗公司 | 2018-02-13 | — | — | CN | disclosed |