Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NT5E | P21589 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 11/20 | 0.40 |
| ▸ | CA1 | P00915 | 7/20 | 0.40 |
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA4 | P22748 | 2/20 | 0.40 |
| ▸ | CA6 | P23280 | 2/20 | 0.40 |
| ▸ | CA5A | P35218 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL776683 | 0.89 | LMNA (0.45) | LMNATSHRALDH1A1NT5ECA2 | |
| SCHEMBL20164792 | 0.87 | CA2 (0.45) | LMNATSHRALDH1A1NT5ECA2 | |
| SCHEMBL775755 | 0.85 | LMNA (0.41) | LMNATSHRALDH1A1NT5ECA2 | |
| SCHEMBL21644984 | 0.84 | CA2 (0.41) | LMNATSHRALDH1A1NT5ECA2 | |
| SCHEMBL10377765 | 0.82 | CA1 (0.41) | LMNATSHRALDH1A1NT5ECA2 | |
| SCHEMBL8916745 | 0.82 | CA2 (0.39) | LMNATSHRALDH1A1NT5ECA2 | |
| SCHEMBL11583429 | 0.81 | LMNA (0.56) | LMNATSHRALDH1A1NT5ECA2 | |
| SCHEMBL658697 | 0.81 | LMNA (0.43) | LMNATSHRALDH1A1NT5ECA2 | |
| SCHEMBL1415343 | 0.81 | F2 (0.40) | TSHRALDH1A1CA2CA1F2 | |
| SCHEMBL776653 | 0.80 | TSHR (0.50) | LMNATSHRALDH1A1NT5ECA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110556509-A | Method for performing surface protection and passivation treatment on metallic lithium cathode by using fluorine-containing organic matter, product and application | NANJING UNIVERSITY OF TECHNOLOGY | 2019-12-10 | — | — | CN | claimed |
| JP-60092260-A | — | — | None | — | — | JP | disclosed |
| WO-2023085390-A1 | LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT | 日産化学株式会社 | 2023-05-19 | — | — | WO | disclosed |
| EP-3438108-B1 | PHENYL [A]INDOLE[2,3-G]QUINOLIZINE COMPOUNDS, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION, AND APPLICATIONS THEREOF | SHANGHAI INST MATERIA MEDICA CAS (CN) | 2022-08-10 | — | — | EP | disclosed |
| CN-112299960-B | Synthesis method and application of bis (2,2, 2-trifluoroethyl) ether | 江苏蓝色星球环保科技股份有限公司 | 2022-03-29 | — | — | CN | disclosed |
| WO-2021249800-A1 | SUBSTITUTED [1,2,4]TRIAZOLE COMPOUNDS AS FUNGICIDES | BASF SE (DE) | 2021-12-16 | — | — | WO | disclosed |
| CN-109071541-B | Phenyl [ a ] indole [2,3-g ] quinolizine compound, preparation method thereof, pharmaceutical composition and application thereof | 中国科学院上海药物研究所 | 2021-06-18 | — | — | CN | disclosed |
| US-10927107-B2 | Phenyl [a]indole[2,3-g]quinolizine compounds, preparation method therefor, pharmaceutical composition, and applications thereof | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2021-02-23 | — | — | US | disclosed |
| CN-112299960-A | Synthesis method and application of bis (2,2, 2-trifluoroethyl) ether | 江苏蓝色星球环保科技股份有限公司 | 2021-02-02 | — | — | CN | disclosed |
| CN-109790145-B | Dihydropyrimidine compound and preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2020-09-22 | — | — | CN | disclosed |
| US-5747424-A | HEATING AN AROMATIC DIKETONE WITH A SALT OF HYDROXYLAMINE IN A SOLVENT | RHONE-POULENC AGRICULTURE LTD. (GB) | 1998-05-05 | — | — | US | disclosed |
| US-5658858-A | POSTEMERGENCE HERBICIDES | RHONE-POULENC ARGRICULTURE LIMITED (GB) | 1997-08-19 | — | — | US | disclosed |
| US-5656573-A | Herbicidal 4-substituted isoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-08-12 | — | — | US | disclosed |
| US-5650533-A | Intermediates to herbicidal 4-substituted isoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-07-22 | — | — | US | disclosed |
| EP-0734380-A1 | 4-BENZOYLISOXAZOLES AND THEIR USE AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1996-10-02 | — | — | EP | disclosed |
| WO-1995016678-A1 | 4-BENZOYLISOXAZOLES AND THEIR USE AS HERBICIDES | RHONE POULENC AGRICULTURE LIMITED (GB) | 1995-06-22 | — | — | WO | disclosed |
| US-4754067-A | REACTING A SYMETRICAL DIAMINOGUANIDINE WITH HYDROXYLAMINE HYDROCHLORIDE | AMERICAN CYANAMID COMPANY (US) | 1988-06-28 | — | — | US | disclosed |
| US-4649148-A | Insecticidal uses of diaminoguanidine hydrazone compounds | AMERICAN CYANAMID COMPANY (US) | 1987-03-10 | — | — | US | disclosed |
| US-4575560-A | ANTIFEEDING AGENTS | AMERICAN CYANAMID COMPANY (US) | 1986-03-11 | — | — | US | disclosed |
| JP-S6092260-A | NOVEL BENZOYLUREA DERIVATIVE, ITS INTERMEDIATE, THEIR PREPARATION AND INSECTICIDE | NIPPON TOKUSHU NOYAKU SEIZO KK | 1985-05-23 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10927107-B2 | Phenyl [a]indole[2,3-g]quinolizine compounds, preparation method therefor, pharmaceutical composition, and applications thereof | PCSK9, PCSK7, PCSK6 | LMNA 474/4885TSHR 3140/4885ALDH1A1 2606/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.