Sugi Predict

Sugi Predict / Compounds / Coprinin

Coprinin

Coprinin

SCHEMBL3416504

COC1=CC(=O)C(C)=CC1=O

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ERBB2 P04626 1/20 0.50
▸ HKDC1 Q2TB90 2/20 0.46
▸ ALOX5 P09917 8/20 0.43
▸ MAPT P10636 5/20 0.43
▸ KDM4E B2RXH2 4/20 0.43
▸ CYP3A4 P08684 4/20 0.43
▸ MEN1 O00255 3/20 0.43
▸ TP53 P04637 3/20 0.43
▸ KMT2A Q03164 3/20 0.43
▸ ALDH1A1 P00352 3/20 0.43
▸ HPGD P15428 3/20 0.43
▸ ALOX15 P16050 3/20 0.43
▸ HSD17B10 Q99714 2/20 0.43
▸ THRB P10828 1/20 0.43
▸ BLM P54132 1/20 0.43
▸ EEF2K O00418 1/20 0.43
▸ PLK1 P53350 1/20 0.43
▸ PLK2 Q9NYY3 1/20 0.43
▸ USP2 O75604 3/20 0.42
▸ MAPK1 P28482 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL49737 0.87 ERBB2 (0.62) ERBB2HKDC1ALOX5MAPTKDM4E
SCHEMBL28856262 0.84 ERBB2 (0.59) ERBB2HKDC1ALOX5MAPTKDM4E
SCHEMBL28259188 0.84 ERBB2 (0.59) ERBB2HKDC1ALOX5MAPTKDM4E
SCHEMBL11025815 0.82 MAPT (0.50) ERBB2HKDC1ALOX5MAPTKDM4E
SCHEMBL10786651 0.79 ERBB2 (0.45) ERBB2HKDC1ALOX5MAPTKDM4E
P-Xyloquinone SCHEMBL49964 0.78 PLK1 (0.60) ERBB2MAPTKDM4ECYP3A4MEN1
SCHEMBL3417111 0.75 HKDC1 (0.56) ERBB2HKDC1ALOX5MAPTKDM4E
SCHEMBL10446570 0.75 PTPRC (0.47) ALOX5MAPTKDM4ECYP3A4MEN1
SCHEMBL23751954 0.73 ERBB2 (0.48) ERBB2HKDC1ALOX5MAPTKDM4E
SCHEMBL17261224 0.73 ERBB2 (0.48) ERBB2HKDC1ALOX5MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220409554-A1 ASCORBIC ACID AND QUINONE COMPOUND FOR CANCER TREATMENT IC-MedTech Corp. 2022-12-29 — — US claimed
EP-1754514-A1 Agent and method for colouring keratin fibres Wella Aktiengesellschaft (DE) 2007-02-21 — — EP claimed
US-20070000073-A1 Agent and method for colouring keratin fibres PROCTER & GAMBLE COMPANY, THE 2007-01-04 — — US claimed
WO-2006094217-A2 AGENT AND METHOD FOR COLOURING KERATIN FIBRES THE PROCTER & GAMBLE COMPANY (US) 2006-09-08 — — WO claimed
US-7070625-B2 Agent and method for coloring keratin fibers containing 2-benzothiazolinone-hydrazone and quinone derivatives WELLA AG (DE) 2006-07-04 — — US claimed
EP-1448540-A1 AGENT AND METHOD FOR COLORING KERATIN FIBERS CONTAINING 2-BENZOTHIAZOLINONE-HYDRAZONE AND QUINONE DERIVATIVES Wella Aktiengesellschaft (DE) 2004-08-25 — — EP claimed
US-20040060124-A1 Agent and method for coloring keratin fibers containing 2-benzothiazolinone-hydrazone and quinone derivatives HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) 2004-04-01 — — US claimed
WO-2003042199-A1 AGENT AND METHOD FOR COLORING KERATIN FIBERS CONTAINING 2-BENZOTHIAZOLINONE-HYDRAZONE AND QUINONE DERIVATIVES WELLA AKTIENGESELLSCHAFT (DE) 2003-05-22 — — WO claimed
US-4246181-A HAIR DYE L'OREAL (FR) 1981-01-20 — — US claimed
US-20240358783-A1 METHOD AND SYSTEM FOR THE TRANSDERMAL ADMINISTRATION OF A PSYCHEDELIC AGENT LCT TECHNOLOGIES LLC 2024-10-31 — — US disclosed
EP-4313007-A1 TRANSDERMAL SYSTEM, FORMULATION, AND METHOD FOR THE THERAPEUTIC ADMINISTRATION OF A PSYCHEDELIC AGENT Lyfe CHNG, LLC (US) 2024-02-07 — — EP disclosed
US-20220409554-A1 ASCORBIC ACID AND QUINONE COMPOUND FOR CANCER TREATMENT IC-MedTech Corp. 2022-12-29 — — US disclosed
WO-2022221072-A1 TRANSDERMAL SYSTEM, FORMULATION, AND METHOD FOR THE THERAPEUTIC ADMINISTRATION OF A PSYCHEDELIC AGENT MYCRODOSE THERAPEUTICS INC. (US) 2022-10-20 — — WO disclosed
WO-2022212789-A1 TRANSDERMAL SYSTEM, FORMULATION, AND METHOD FOR THE THERAPEUTIC ADMINISTRATION OF A PSYCHEDELIC AGENT MYCRODOSE THERAPEUTICS INC. (US) 2022-10-06 — — WO disclosed
US-4204059-A HAIR DYES L'OREAL (FR) 1980-05-20 — — US disclosed
US-4084052-A HAIR DYES L'OREAL (FR) 1978-04-11 — — US disclosed
US-4067869-A HAIR DYES L'OREAL (FR) 1978-01-10 — — US disclosed
US-4023926-A Diaminobenzoquinones in hair dye compositions SOCIETE ANONYME DITE: L'OREAL (FR) 1977-05-17 — — US disclosed
US-3997546-A HAIR DYE SOCIETE ANONYME DITE: L'OREAL (FR) 1976-12-14 — — US disclosed
US-3966722-A Indamines for dyeing keratinous fibers L'OREAL (FR) 1976-06-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240358783-A1 METHOD AND SYSTEM FOR THE TRANSDERMAL ADMINISTRATION OF A PSYCHEDELIC AGENT HTR7, HTR6, PNMT ERBB2 1923/4885HKDC1 763/4885ALOX5 2183/4885
US-20040060124-A1 Agent and method for coloring keratin fibers containing 2-benzothiazolinone-hydrazone and quinone derivatives KRT18, NDUFA1, NDUFA2 ERBB2 1732/4885HKDC1 36/4885ALOX5 4244/4885
US-20070000073-A1 Agent and method for colouring keratin fibres KRT18, CDC73, OAT ERBB2 2967/4885HKDC1 28/4885ALOX5 4492/4885
US-20220409554-A1 ASCORBIC ACID AND QUINONE COMPOUND FOR CANCER TREATMENT NQO1, SDHB, SDHA ERBB2 4158/4885HKDC1 803/4885ALOX5 265/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.