SCHEMBL28856293

SCHEMBL28856293

BrNNc1cc(Br)ccc1Br

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.44
TLR9 Q9NR96 1/20 0.44
ALDH1A1 P00352 3/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
ALOX15 P16050 2/20 0.37
TSHR P16473 2/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
GAA P10253 1/20 0.37
CYP2C9 P11712 1/20 0.37
PKM P14618 1/20 0.37
LMNA P02545 1/20 0.37
THRB P10828 1/20 0.37
BLM P54132 1/20 0.37
BTK Q06187 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
PLK3 Q9H4B4 1/20 0.37
MAPK1 P28482 2/20 0.34
S100A4 P26447 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28200158 0.98 HSP90AA1 (0.43) HSP90AA1TLR9ALDH1A1MEN1KMT2A
Oxalic Acid SCHEMBL28200792 0.88 ALDH1A1 (0.44) HSP90AA1TLR9ALDH1A1MEN1KMT2A
Sulfuric Acid SCHEMBL28200108 0.88 HSP90AA1 (0.41) HSP90AA1TLR9ALDH1A1MEN1KMT2A
Phosphoric Acid SCHEMBL28200101 0.88 HSP90AA1 (0.41) HSP90AA1TLR9ALDH1A1MEN1KMT2A
SCHEMBL28200173 0.81 ALOX15 (0.41) HSP90AA1TLR9ALDH1A1MEN1KMT2A
Hydrochloric Acid SCHEMBL28200736 0.79 ALOX15 (0.39) HSP90AA1TLR9ALDH1A1MEN1KMT2A
SCHEMBL20984668 0.74 GAA (0.50) HSP90AA1TLR9ALDH1A1MEN1KMT2A
SCHEMBL9983346 0.73 HSP90AA1 (0.41) HSP90AA1TLR9ALDH1A1MEN1KMT2A
SCHEMBL29661763 0.73 ALDH1A1 (0.41) HSP90AA1TLR9ALDH1A1MEN1KMT2A
SCHEMBL19735030 0.73 ALDH1A1 (0.41) HSP90AA1TLR9ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107663161-A A kind of continuous stream synthesis technique of phenylhydrazine salt and substituted benzene hydrazonium salt 上海惠和化德生物科技有限公司 2018-02-06 CN disclosed