Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 5/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.32 |
| ▸ | PDE5A | O76074 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | PRKDC | P78527 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | ATR | Q13535 | 1/20 | 0.32 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28856557 | 0.90 | SLC22A12 (0.34) | SLC22A12ATMCDK9KDM4EALDH1A1 | |
| SCHEMBL28856483 | 0.87 | SMN1; SMN2 (0.34) | SLC22A12HCRTR1HCRTR2ATMKDM4E | |
| SCHEMBL28856484 | 0.87 | MAPT (0.40) | IDO1ATMCDK9KDM4E | |
| SCHEMBL28856509 | 0.87 | SLC22A12 (0.41) | SLC22A12CDK8ABL1IDO1TDO2 | |
| SCHEMBL28856533 | 0.86 | SLC22A12 (0.36) | SLC22A12CDK9KDM4EALDH1A1HPGD | |
| SCHEMBL28856505 | 0.85 | ALDH1A1 (0.35) | ACVR1KDM4EALDH1A1HPGD | |
| SCHEMBL28954999 | 0.82 | SLC22A12 (0.34) | SLC22A12KDM4EALDH1A1HPGD | |
| SCHEMBL28856503 | 0.82 | MAPK1 (0.34) | SLC22A12CDK9KDM4EALDH1A1HPGD | |
| SCHEMBL28856485 | 0.81 | SLC22A12 (0.35) | SLC22A12ATMKDM4EALDH1A1HPGD | |
| SCHEMBL28856508 | 0.78 | SLC22A12 (0.39) | SLC22A12ABL1ACVR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109608432-B | Thiophene derivatives as URAT1 inhibitors | 江苏艾立康医药科技有限公司 | 2022-10-11 | — | — | CN | disclosed |