Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.32 |
| ▸ | PRNP | P04156 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | PPOX | P50336 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28856519 | 0.87 | SLC22A12 (0.38) | ALDH1A1HPGDTDP1TP53PPARA | |
| SCHEMBL28856529 | 0.86 | TP53 (0.33) | ALDH1A1HPGDTDP1TP53PPARA | |
| SCHEMBL28856520 | 0.85 | SLC22A12 (0.39) | ALDH1A1HPGDTDP1TP53PPARA | |
| SCHEMBL28856548 | 0.84 | PPARA (0.47) | PPARASLC22A12 | |
| SCHEMBL28856524 | 0.82 | SLC22A12 (0.44) | MAPTSLC22A12 | |
| SCHEMBL28856493 | 0.81 | SLC22A12 (0.38) | ALDH1A1HPGDTP53KDM4ESLC22A12 | |
| SCHEMBL28856515 | 0.80 | SLC22A12 (0.43) | ALDH1A1TP53PRNPSLC22A12 | |
| SCHEMBL28856492 | 0.71 | PPARA (0.48) | PPARASLC22A12 | |
| SCHEMBL28856538 | 0.71 | SLC22A12 (0.53) | ALDH1A1HPGDPPARAMAPTSLC22A12 | |
| SCHEMBL28856512 | 0.70 | PPARA (0.41) | ALDH1A1TP53PPARAPIN1MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109608432-B | Thiophene derivatives as URAT1 inhibitors | 江苏艾立康医药科技有限公司 | 2022-10-11 | — | — | CN | disclosed |