Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 4/20 | 0.38 |
| ▸ | CA2 | P00918 | 4/20 | 0.38 |
| ▸ | CA9 | Q16790 | 4/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 7/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | PRNP | P04156 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29896764 | 0.88 | ALDH1A1 (0.36) | SLC22A12TP53ALDH1A1PTGDR2 | |
| SCHEMBL28856556 | 0.88 | ALDH1A1 (0.36) | SLC22A12TP53ALDH1A1PTGDR2 | |
| SCHEMBL29896755 | 0.86 | AAK1 (0.39) | AAK1 | |
| SCHEMBL28856550 | 0.86 | SMN1; SMN2 (0.37) | SLC22A12TP53ALDH1A1PRNP | |
| SCHEMBL28856498 | 0.86 | AAK1 (0.39) | AAK1 | |
| SCHEMBL28856545 | 0.86 | PPOX (0.37) | SLC22A12TP53ALDH1A1PRNP | |
| SCHEMBL29896802 | 0.86 | SMN1; SMN2 (0.37) | SLC22A12TP53ALDH1A1PRNP | |
| SCHEMBL28856531 | 0.85 | SLC22A12 (0.58) | SLC22A12CA12CA1CA2CA9 | |
| SCHEMBL28856519 | 0.84 | SLC22A12 (0.38) | SLC22A12TP53ALDH1A1PRNP | |
| SCHEMBL28856529 | 0.83 | TP53 (0.33) | SLC22A12TP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109608432-B | Thiophene derivatives as URAT1 inhibitors | 江苏艾立康医药科技有限公司 | 2022-10-11 | — | — | CN | disclosed |