Triclofenol

Triclofenol

SCHEMBL29387498

Oc1cc(Cl)c(Cl)cc1Cl

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HSD17B10 Q99714 11/20 1.00
▸ TSHR P16473 8/20 1.00
▸ HPGD P15428 7/20 1.00
▸ CYP3A4 P08684 5/20 0.55
▸ ALDH1A1 P00352 5/20 0.55
▸ TDP1 Q9NUW8 1/20 0.55
▸ HSP90AA1 P07900 1/20 0.50
▸ CASP1 P29466 1/20 0.47
▸ MAPK1 P28482 3/20 0.44
▸ AHR P35869 1/20 0.44
▸ CA1 P00915 1/20 0.43
▸ CA2 P00918 1/20 0.43
▸ CRHBP P24387 1/20 0.40
▸ CRHR2 Q13324 1/20 0.40
▸ TTR P02766 1/20 0.40
▸ RECQL P46063 1/20 0.40
▸ ADRA1A P35348 1/20 0.40
▸ TP53 P04637 1/20 0.40
▸ ESR2 Q92731 1/20 0.39
▸ ALOX15 P16050 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Triclofenol SCHEMBL1338 1.00 HSD17B10 (1.00) HSD17B10TSHRHPGDCYP3A4ALDH1A1
Triclofenol SCHEMBL2813598 0.97 HSD17B10 (0.93) HSD17B10TSHRHPGDCYP3A4ALDH1A1
SCHEMBL48305 0.93 HSD17B10 (0.86) HSD17B10TSHRHPGDCYP3A4ALDH1A1
SCHEMBL69259 0.89 HSD17B10 (0.80) HSD17B10TSHRHPGDCYP3A4ALDH1A1
SCHEMBL6861156 0.88 HSD17B10 (0.78) HSD17B10TSHRHPGDCYP3A4ALDH1A1
Triclofenol SCHEMBL28856638 0.86 HSD17B10 (0.74) HSD17B10TSHRHPGDCYP3A4ALDH1A1
Pentachlorophenol SCHEMBL9036678 0.86 HSD17B10 (0.74) HSD17B10TSHRHPGDCYP3A4ALDH1A1
SCHEMBL592892 0.86 HSD17B10 (0.75) HSD17B10TSHRHPGDCYP3A4ALDH1A1
SCHEMBL70334 0.85 HSD17B10 (0.73) HSD17B10TSHRHPGDCYP3A4ALDH1A1
SCHEMBL29402084 0.85 HSD17B10 (0.73) HSD17B10TSHRHPGDCYP3A4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260092924-A1 NON-ENZYMATIC GLOW ASSAYS UNIVERSITY OF HOUSTON SYSTEM (US) 2026-04-02 — — US claimed
CN-116426547-B Artificial transformation 2,4-dichlorophenol hydroxylase gene and application thereof 海南师范大学 2023-10-03 — — CN claimed
CN-116426547-A Artificial transformation 2,4-dichlorophenol hydroxylase gene and application thereof 海南师范大学 2023-07-14 — — CN claimed
US-20260092924-A1 NON-ENZYMATIC GLOW ASSAYS UNIVERSITY OF HOUSTON SYSTEM (US) 2026-04-02 — — US disclosed
EP-3877753-B1 NON-ENZYMATIC GLOW ASSAYS UNIV HOUSTON SYSTEM (US) 2025-10-08 — — EP disclosed
US-12391580-B2 Use of basalt for adsorbing toxic material BELL, TOMARO 2025-08-19 — — US disclosed
US-12391579-B2 Basalt fiber for adsorbing toxic material BELL, TOMARO 2025-08-19 — — US disclosed
US-12384696-B2 Use of basalt fiber to adsorb toxic material BELL, TOMARO 2025-08-12 — — US disclosed
WO-2025129358-A1 STABLE FILM FORMULATIONS FOR HIGH LOADING OF LOW MELTING POINT ACTIVES INTELGENX CORP. (CA) 2025-06-26 — — WO disclosed
CN-118909990-B Novel trichlorophenol degrading enzyme and application thereof 安徽农业大学 2025-01-21 — — CN disclosed
CN-115774070-B Method for simultaneously measuring 19 chlorophenols in aquatic product 宁波市产品食品质量检验研究院(宁波市纤维检验所) 2025-01-03 — — CN disclosed
US-20240294400-A1 BASALT FIBER FOR ADSORBING TOXIC MATERIAL BELL, TOMARO 2024-09-05 — — US disclosed
US-12037264-B2 Use of basalt to adsorb toxic material BELL, TOMARO 2024-07-16 — — US disclosed
EP-3515589-B1 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2024-02-14 — — EP disclosed
CN-116426547-B Artificial transformation 2,4-dichlorophenol hydroxylase gene and application thereof 海南师范大学 2023-10-03 — — CN disclosed
CN-116426547-A Artificial transformation 2,4-dichlorophenol hydroxylase gene and application thereof 海南师范大学 2023-07-14 — — CN disclosed
CN-115808479-A Method for simultaneously measuring 19 chlorophenol compounds in fish meat based on UPLC-Q-TOF-MS method 宁波市产品食品质量检验研究院(宁波市纤维检验所) 2023-03-17 — — CN disclosed
CN-115774070-A Method for simultaneously measuring 19 chlorophenol compounds in aquatic product 宁波市产品食品质量检验研究院(宁波市纤维检验所) 2023-03-10 — — CN disclosed
CN-114058519-A Organic pollutant and straw degradation promoter and application thereof 浙江工业大学 2022-02-18 — — CN disclosed
US-20220047505-A1 Controlled Absorption Water-Soluble Pharmaceutically Active Organic Compound Formulation for Once-Daily Administration STI PHARMA, LLC (US) 2022-02-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260092924-A1 NON-ENZYMATIC GLOW ASSAYS LPO, HAO2, PPOX HSD17B10 1044/4885TSHR 1094/4885HPGD 1256/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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