Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.43 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28857648 | 0.90 | HDAC3 (0.46) | MGLLPOLB | |
| SCHEMBL28857581 | 0.88 | LMNA (0.48) | MGLLPOLBHTTLMNAMAPT | |
| SCHEMBL29898240 | 0.88 | LMNA (0.48) | MGLLPOLBHTTLMNAMAPT | |
| SCHEMBL28857620 | 0.86 | TNIK (0.49) | POLBHTTLMNASMN1; SMN2MAPT | |
| SCHEMBL29898258 | 0.83 | POLB (0.49) | POLBHTTLMNASMN1; SMN2MAPT | |
| SCHEMBL28857616 | 0.83 | POLB (0.49) | POLBHTTLMNASMN1; SMN2MAPT | |
| SCHEMBL28857590 | 0.83 | POLB (0.51) | POLBHTTLMNASMN1; SMN2MAPT | |
| SCHEMBL28857641 | 0.83 | SMN1; SMN2 (0.51) | POLBHTTLMNASMN1; SMN2 | |
| SCHEMBL28857607 | 0.82 | SMN1; SMN2 (0.46) | POLBHTTLMNASMN1; SMN2HPGD | |
| SCHEMBL29898221 | 0.82 | SMN1; SMN2 (0.46) | POLBHTTLMNASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115160269-A | Arylcarboxamide derivatives as positive allosteric modulators of NMDAR | 北京大学 | 2022-10-11 | — | — | CN | claimed |
| CN-115160269-A | Arylcarboxamide derivatives as positive allosteric modulators of NMDAR | 北京大学 | 2022-10-11 | — | — | CN | disclosed |