Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 5/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.62 |
| ▸ | GAA | P10253 | 3/20 | 0.62 |
| ▸ | RAB9A | P51151 | 5/20 | 0.60 |
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | MITF | O75030 | 1/20 | 0.55 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.55 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.55 |
| ▸ | DHODH | Q02127 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23259605 | 0.85 | PKM (0.76) | PKMALDH1A1HTTSMN1; SMN2GAA | |
| SCHEMBL6933566 | 0.82 | CYP1A2 (0.61) | PKMALDH1A1HTTSMN1; SMN2GAA | |
| SCHEMBL6638142 | 0.80 | ATM (0.77) | PKMALDH1A1HTTSMN1; SMN2GAA | |
| SCHEMBL20188060 | 0.80 | TSHR (0.74) | ALDH1A1HTTSMN1; SMN2GAARAB9A | |
| SCHEMBL7716932 | 0.79 | ALDH1A1 (1.00) | PKMALDH1A1HTTSMN1; SMN2GAA | |
| SCHEMBL28857631 | 0.78 | POLB (0.58) | PKMALDH1A1HTTSMN1; SMN2GAA | |
| SCHEMBL28988455 | 0.78 | ATM (0.78) | PKMALDH1A1HTTSMN1; SMN2GAA | |
| SCHEMBL28857606 | 0.77 | POLB (0.57) | PKMALDH1A1HTTSMN1; SMN2GAA | |
| SCHEMBL15789123 | 0.76 | DHODH (0.72) | ALDH1A1RAB9ANPC1TP53MAPT | |
| SCHEMBL29434785 | 0.76 | DHODH (0.72) | ALDH1A1RAB9ANPC1TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115160269-A | Arylcarboxamide derivatives as positive allosteric modulators of NMDAR | 北京大学 | 2022-10-11 | — | — | CN | claimed |
| CN-115160269-A | Arylcarboxamide derivatives as positive allosteric modulators of NMDAR | 北京大学 | 2022-10-11 | — | — | CN | disclosed |