Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.58 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.58 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.58 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6357310 | 0.91 | SIRT6 (0.65) | CYP1A2SMN1; SMN2NPC1RAB9AAKR1C4 | |
| SCHEMBL6348632 | 0.89 | MEN1 (0.69) | RAB9AAKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL21701478 | 0.83 | CYP1A2 (0.61) | CYP1A2SMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL14075179 | 0.83 | LTC4S (0.66) | CYP1A2SMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL6815137 | 0.83 | GFER (0.71) | CYP1A2SMN1; SMN2RAB9AKMT2ALMNA | |
| SCHEMBL28857643 | 0.82 | PKM (0.72) | SMN1; SMN2NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL15528812 | 0.81 | MAPK1 (0.71) | CYP1A2SMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL6814636 | 0.80 | CYP1A2 (0.57) | CYP1A2RAB9AKMT2ALMNAALDH1A1 | |
| SCHEMBL6816902 | 0.79 | ALDH1A1 (0.72) | CYP1A2SMN1; SMN2NPC1RAB9AAKR1C4 | |
| SCHEMBL6835903 | 0.79 | ALDH1A1 (0.70) | SMN1; SMN2NPC1RAB9AAKR1C4AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | GABRD, GABBR1, GABRA1 | CYP1A2 710/4885SMN1; SMN2 2022/4885NPC1 3778/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.