SCHEMBL20188060

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6638013	0.82	TSHR (0.73)	TSHRKMT2AHSD17B10KDM4EHPGD
	SCHEMBL20201167	0.81	KMT2A (0.51)	TSHRKMT2AHSD17B10KDM4EHPGD
	SCHEMBL28857643	0.80	PKM (0.72)	KDM4ESMN1; SMN2HTTMAPTALDH1A1
	SCHEMBL21880903	0.77	RAB9A (1.00)	TSHRKMT2AHSD17B10KDM4EHPGD
	SCHEMBL12214430	0.77	RAB9A (1.00)	TSHRKMT2AHSD17B10KDM4EHPGD
	SCHEMBL7294117	0.76	KDM4E (0.81)	TSHRKMT2AHSD17B10KDM4EHPGD
	SCHEMBL6933566	0.76	CYP1A2 (0.61)	TSHRKMT2AHSD17B10KDM4EHPGD
	SCHEMBL2322923	0.75	KMT2A (0.53)	TSHRKMT2AHSD17B10KDM4ESMN1; SMN2
	SCHEMBL14721362	0.75	ALDH1A1 (0.52)	TSHRKMT2AHSD17B10KDM4ESMN1; SMN2
	SCHEMBL20187795	0.75	KMT2A (0.47)	TSHRKMT2AHSD17B10KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.