Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGMS2 | Q8NHU3 | 3/20 | 0.82 |
| ▸ | MEN1 | O00255 | 3/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.80 |
| ▸ | PPIA | P62937 | 1/20 | 0.65 |
| ▸ | CNR2 | P34972 | 3/20 | 0.58 |
| ▸ | CNR1 | P21554 | 2/20 | 0.58 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29908365 | 0.88 | SGMS2 (0.67) | SGMS2MEN1KMT2AALDH1A1PPIA | |
| SCHEMBL8035583 | 0.83 | SGMS2 (0.58) | SGMS2MEN1KMT2AALDH1A1PPIA | |
| SCHEMBL8037216 | 0.83 | SGMS2 (0.58) | SGMS2MEN1KMT2AALDH1A1PPIA | |
| SCHEMBL8035606 | 0.82 | SGMS2 (0.56) | SGMS2MEN1KMT2AALDH1A1CNR2 | |
| SCHEMBL8041228 | 0.79 | SGMS2 (0.53) | SGMS2MEN1KMT2AALDH1A1PPIA | |
| SCHEMBL27817521 | 0.79 | PPIA (1.00) | SGMS2MEN1KMT2AALDH1A1PPIA | |
| SCHEMBL28397953 | 0.78 | MEN1 (0.79) | SGMS2MEN1KMT2AALDH1A1PPIA | |
| SCHEMBL8038995 | 0.78 | ALDH1A1 (0.52) | SGMS2MEN1KMT2AALDH1A1PPIA | |
| SCHEMBL8037213 | 0.77 | MEN1 (0.51) | SGMS2MEN1KMT2AALDH1A1PPIA | |
| SCHEMBL4147984 | 0.75 | SGMS2 (0.67) | SGMS2MEN1KMT2AALDH1A1PPIA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115028679-B | PROTAC compound with Cyclophilin A degradation activity and preparation method and application thereof | 深圳湾实验室 | 2022-11-15 | — | — | CN | disclosed |
| CN-115028679-A | PROTAC compound with Cyclophilin A degradation activity and preparation method and application thereof | 深圳湾实验室 | 2022-09-09 | — | — | CN | disclosed |