Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 2/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | PPIA | P62937 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8037216 | 1.00 | SGMS2 (0.58) | SGMS2ALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL8037213 | 0.95 | MEN1 (0.51) | SGMS2ALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL8035606 | 0.89 | SGMS2 (0.56) | SGMS2ALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL8041228 | 0.86 | SGMS2 (0.53) | SGMS2ALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL8038995 | 0.85 | ALDH1A1 (0.52) | SGMS2ALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL8037325 | 0.83 | NPC1 (0.47) | ALDH1A1MEN1KMT2ANPC1PPIA | |
| SCHEMBL28857791 | 0.83 | SGMS2 (0.82) | SGMS2ALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL8039095 | 0.83 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2ANPC1PPIA | |
| SCHEMBL8041285 | 0.81 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2ANPC1LMNA | |
| SCHEMBL8025483 | 0.81 | MEN1 (0.46) | SGMS2ALDH1A1MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081892-A1 | NOVEL CATECHOL DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, AND USE OF THOSE | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-07-02 | — | — | WO | disclosed |