Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL121529 | 0.88 | CHRM2 (0.70) | CHRM2ALDH1A1POLBKDM4EHTT | |
| Hydrochloric Acid SCHEMBL9479560 | 0.86 | CHRM2 (0.68) | CHRM2ALDH1A1POLBKDM4EHTT | |
| Hydrochloric Acid SCHEMBL2147064 | 0.86 | CHRM2 (0.68) | CHRM2ALDH1A1POLBKDM4EHTT | |
| SCHEMBL22305119 | 0.82 | CHRM2 (0.63) | CHRM2ALDH1A1POLBKDM4EHTT | |
| SCHEMBL9864385 | 0.82 | TAAR1 (0.57) | ALDH1A1KDM4E | |
| SCHEMBL542479 | 0.82 | LTA4H (0.63) | ALDH1A1KDM4ESMN1; SMN2TP53 | |
| SCHEMBL2185129 | 0.81 | MAPT (0.65) | ALDH1A1KDM4EPKMGAA | |
| SCHEMBL3842580 | 0.81 | ALDH1A1 (0.52) | CHRM2ALDH1A1POLBKDM4EHTT | |
| SCHEMBL12602529 | 0.80 | ACHE (0.62) | CHRM2ALDH1A1POLBKDM4EHTT | |
| SCHEMBL1279045 | 0.80 | HTT (0.73) | CHRM2ALDH1A1POLBKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922419-A | Imidazo [1,2 B] [1,2,4] pyrrolotriazine derivatives as antiparasitic agent | 葛兰素史密斯克莱知识产权发展有限公司 | 2018-04-17 | — | — | CN | disclosed |