SCHEMBL2885900

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2884492	0.94	HPGD (0.51)	HPGDPGRCYP11B2KDM4EMEN1
	SCHEMBL2879118	0.91	PGR (0.44)	HPGDPGRCYP11B2PLK4DAPK3
	SCHEMBL2881720	0.88	PGR (0.41)	PGRCYP11B2PLK4DAPK3JAK2
	SCHEMBL10095451	0.86	PGR (0.44)	PGRCYP11B2PLK4DAPK3JAK2
	SCHEMBL14468112	0.86	HPGD (0.46)	HPGDPGRPLK4DAPK3JAK2
	SCHEMBL10096613	0.84	CYP11B2 (0.44)	HPGDPGRCYP11B2KDM4EALDH1A1
	SCHEMBL10096179	0.83	PGR (0.42)	PGRCYP11B2PLK4DAPK3JAK2
	SCHEMBL1032219	0.83	PGR (0.42)	PGRCYP11B2PLK4DAPK3JAK2
	SCHEMBL2884063	0.83	KDM4E (0.41)	HPGDKDM4EMEN1KMT2APTGER4
	SCHEMBL12106626	0.82	PGR (0.44)	PGRCYP11B2PLK4DAPK3JAK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.