SCHEMBL1032219

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL980792	0.94	CYP11B2 (0.42)	PGRCYP11B2BRD4PFKFB2NSD2
	SCHEMBL10096224	0.92	CYP11B2 (0.38)	PGRCYP11B2PFKFB2NSD2PFKFB1
	SCHEMBL10095848	0.90	PGR (0.38)	PGRCYP11B2BRD4BRAFPLK4
	SCHEMBL10096179	0.89	PGR (0.42)	PGRCYP11B2BRD4BRAFPLK4
	SCHEMBL10095451	0.89	PGR (0.44)	PGRCYP11B2BRD4BRAFPLK4
	SCHEMBL10096169	0.89	PGR (0.41)	PGRCYP11B2BRD4BRAFPLK4
	SCHEMBL10096229	0.88	PGR (0.39)	PGRCYP11B2BRD4PFKFB2NSD2
	SCHEMBL10095696	0.88	CYP11B2 (0.43)	PGRCYP11B2BRD4NR3C1NR3C2
	SCHEMBL10095975	0.88	CYP11B2 (0.42)	PGRCYP11B2BRD4PFKFB2NSD2
	SCHEMBL10095722	0.87	PGR (0.41)	PGRCYP11B2BRD4BRAFPLK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.