Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28038900 | 0.82 | CYP3A4 (0.43) | L3MBTL1GSTO1TSHRNPSR1ALDH1A1 | |
| SCHEMBL23217979 | 0.81 | ALDH1A1 (0.40) | L3MBTL1GSTO1TSHRNPSR1KDM4E | |
| SCHEMBL29009658 | 0.81 | L3MBTL1 (0.38) | L3MBTL1GSTO1TSHRBCL2A1NPSR1 | |
| SCHEMBL29096379 | 0.78 | STAT5B (0.39) | BCL2A1MEN1KMT2A | |
| SCHEMBL6207086 | 0.77 | L3MBTL1 (0.33) | L3MBTL1GSTO1TSHRNPSR1KDM4E | |
| SCHEMBL3221801 | 0.74 | POLB (0.40) | L3MBTL1GSTO1TSHRKDM4EALDH1A1 | |
| SCHEMBL15466723 | 0.74 | SSTR4 (0.35) | L3MBTL1GSTO1TSHRNPSR1KDM4E | |
| SCHEMBL6205322 | 0.73 | TSHR (0.34) | L3MBTL1GSTO1TSHR | |
| SCHEMBL20297003 | 0.73 | L3MBTL1 (0.35) | L3MBTL1GSTO1TSHRNPSR1KDM4E | |
| SCHEMBL6207594 | 0.73 | L3MBTL1 (0.33) | L3MBTL1TSHRNPSR1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115043788-A | Trifluoromethyl oxazole-2-ketone compound and preparation method and application thereof | 南京工业大学 | 2022-09-13 | — | — | CN | claimed |
| CN-115043788-B | Trifluoromethyl oxazol-2-one compound and preparation method and application thereof | 南京工业大学 | 2023-10-20 | — | — | CN | disclosed |