Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6207594 | 0.86 | L3MBTL1 (0.33) | L3MBTL1TSHRALDH1A1NPSR1KDM4E | |
| SCHEMBL6205322 | 0.84 | TSHR (0.34) | L3MBTL1TSHRGSTO1 | |
| SCHEMBL29009658 | 0.82 | L3MBTL1 (0.38) | L3MBTL1TSHRGSTO1ALDH1A1NPSR1 | |
| SCHEMBL20297003 | 0.82 | L3MBTL1 (0.35) | L3MBTL1TSHRGSTO1CTSSCTSK | |
| SCHEMBL8320869 | 0.81 | TSHR (0.35) | L3MBTL1TSHRALDH1A1KDM4EMEN1 | |
| SCHEMBL28038900 | 0.78 | CYP3A4 (0.43) | L3MBTL1TSHRGSTO1ALDH1A1NPSR1 | |
| SCHEMBL23217979 | 0.77 | ALDH1A1 (0.40) | L3MBTL1TSHRGSTO1CTSSCTSK | |
| SCHEMBL28859253 | 0.77 | L3MBTL1 (0.36) | L3MBTL1TSHRGSTO1ALDH1A1NPSR1 | |
| SCHEMBL6324123 | 0.74 | L3MBTL1 (0.40) | L3MBTL1ALDH1A1NPSR1KDM4EHPGD | |
| SCHEMBL16141841 | 0.74 | L3MBTL1 (0.38) | L3MBTL1TSHRNPSR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0938474-B1 | CYCLOPROPYLINDOLE COMPOUNDS AND THEIR USE AS PRODRUGS | AUCKLAND UNISERVICES LTD (NZ) | 2005-11-23 | — | — | EP | disclosed |
| US-6130237-A | Condensed N-aclyindoles as antitumor agents | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 2000-10-10 | — | — | US | disclosed |