Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.82 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 2/20 | 0.46 |
| ▸ | MGLL | Q99685 | 2/20 | 0.46 |
| ▸ | MELK | Q14680 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.45 |
| ▸ | MINK1 | Q8N4C8 | 2/20 | 0.45 |
| ▸ | TNIK | Q9UKE5 | 2/20 | 0.45 |
| ▸ | FYN | P06241 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1535 | 0.91 | ENPP2 (1.00) | ENPP2PTGS2LMNACA12CA1 | |
| SCHEMBL7940666 | 0.84 | ENPP2 (0.86) | ENPP2PTGS2LMNACA12CA1 | |
| SCHEMBL388018 | 0.84 | ENPP2 (0.86) | ENPP2PTGS2LMNACA12CA1 | |
| SCHEMBL9189840 | 0.83 | ENPP2 (0.75) | ENPP2PTGS2LMNACA12CA1 | |
| Methylphenylsulfone SCHEMBL28225187 | 0.79 | PTGS2 (0.53) | ENPP2PTGS2 | |
| SCHEMBL7937506 | 0.78 | ENPP2 (0.75) | ENPP2PTGS2LMNAGAAPKM | |
| SCHEMBL3468270 | 0.78 | ENPP2 (0.75) | ENPP2PTGS2LMNAFAAHMGLL | |
| SCHEMBL9011046 | 0.78 | ENPP2 (0.75) | ENPP2PTGS2LMNACA12CA1 | |
| SCHEMBL7938035 | 0.78 | ENPP2 (0.75) | ENPP2PTGS2LMNACA12CA1 | |
| SCHEMBL5355231 | 0.78 | ENPP2 (0.75) | ENPP2PTGS2LMNACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114875004-A | High stereoselectivity R transketolase mutant and coding gene and application thereof | 上海交通大学 | 2022-08-09 | — | — | CN | disclosed |