Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 6/20 | 0.42 |
| ▸ | RAF1 | P04049 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | RET | P07949 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | MLYCD | O95822 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.38 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14278745 | 0.80 | RAB9A (0.50) | HTTSMN1; SMN2MEN1KMT2APARP1 | |
| SCHEMBL29177412 | 0.77 | GAA (0.44) | RXFP1GAAMEN1KMT2AKCNK3 | |
| SCHEMBL12480284 | 0.76 | ANO1 (0.47) | RXFP1HTTGAAKCNK3KCNK9 | |
| SCHEMBL15391362 | 0.74 | MLYCD (0.57) | NAMPTMLYCDHTTSMN1; SMN2GAA | |
| SCHEMBL4783765 | 0.73 | SMN1; SMN2 (0.54) | HTTSMN1; SMN2GAAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL20378179 | 0.72 | EPHX2 (0.43) | — | |
| Hydrochloric Acid SCHEMBL20378176 | 0.72 | EPHX2 (0.43) | — | |
| SCHEMBL22819921 | 0.71 | RXFP1 (0.61) | NAMPTRXFP1BRAFKCNK3KCNK9 | |
| SCHEMBL29739342 | 0.70 | NPC1 (0.52) | RXFP1GAAMEN1KMT2ATRPV1 | |
| SCHEMBL18554430 | 0.70 | EPHX2 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108024992-A | Aryl, Heteroaryl and Heterocyclic Compounds for the Treatment of Medical Disorders | 艾其林医药公司 | 2018-05-11 | — | — | CN | disclosed |