Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.42 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPY1R | P25929 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPY2R | P49146 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6696278 | 0.87 | FFAR4 (0.43) | FFAR4ALOX5APFEN1RAB9ANPC1 | |
| SCHEMBL4936414 | 0.87 | FFAR4 (0.53) | FFAR4RAB9ANPC1SMN1; SMN2PPARG | |
| SCHEMBL2886631 | 0.81 | FFAR4 (0.46) | FFAR4PPARDPPARACNR1CNR2 | |
| SCHEMBL2889790 | 0.79 | FFAR4 (0.41) | FFAR4ALOX5APFEN1RAB9ALMNA | |
| SCHEMBL4936500 | 0.78 | FFAR4 (0.57) | FFAR4PPARA | |
| SCHEMBL2889244 | 0.76 | FFAR4 (0.46) | FFAR4HTR2A | |
| SCHEMBL2985236 | 0.74 | HTR2A (0.58) | LMNASMN1; SMN2KDM4ENPY1RHTT | |
| SCHEMBL2890267 | 0.72 | HTR2A (0.47) | RAB9ANPC1LMNASMN1; SMN2KDM4E | |
| SCHEMBL2987073 | 0.72 | BCHE (0.57) | RAB9ANPC1LMNASMN1; SMN2KDM4E | |
| SCHEMBL2293341 | 0.72 | BCHE (0.55) | RAB9ANPC1LMNASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7700653-B2 | Halogen-substituted aminodicarboxylic acid derivatives | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-04-20 | — | — | US | disclosed |
| US-7700653-B2 | Halogen-substituted aminodicarboxylic acid derivatives | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-04-20 | — | — | US | disclosed |
| US-7700653-B2 | Halogen-substituted aminodicarboxylic acid derivatives | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-04-20 | — | — | US | disclosed |
| US-7067694-B2 | Halogen-substituted amino dicarboxylic acid derivatives as medicaments for treating cardiovascular diseases | BAYER AKTIENGESELLSCHAFT (DE) | 2006-06-27 | — | — | US | disclosed |
| US-20060111444-A1 | Novel halogen-substituted aminodicarboxylic acid derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2006-05-25 | — | — | US | disclosed |
| US-20040092593-A1 | Halogen-substituted amino dicarboxylic acid derivatives as medicaments for treating cardiovascular diseases | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2004-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092593-A1 | Halogen-substituted amino dicarboxylic acid derivatives as medicaments for treating cardiovascular diseases | BCAT2, DDC, AADAT | FFAR4 321/4885ALOX5AP 2757/4885FEN1 3738/4885 |
| US-20060111444-A1 | Novel halogen-substituted aminodicarboxylic acid derivatives | FABP3, PPARD, FABP1 | FFAR4 45/4885ALOX5AP 371/4885FEN1 4154/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.