Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 6/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 4/20 | 0.37 |
| ▸ | CNR2 | P34972 | 4/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.36 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.36 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2889244 | 0.85 | FFAR4 (0.46) | FFAR4HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2885997 | 0.81 | FFAR4 (0.42) | FFAR4CNR1CNR2TRPV6PPARD | |
| SCHEMBL2889457 | 0.74 | SLC6A2 (0.43) | FFAR4HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2888198 | 0.71 | FFAR4 (0.50) | FFAR4FFAR1 | |
| SCHEMBL2888268 | 0.71 | MAOA (0.45) | FFAR4HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6700407 | 0.71 | FFAR4 (0.50) | FFAR4HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2888269 | 0.71 | MAOA (0.45) | FFAR4HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6697870 | 0.70 | FFAR4 (0.47) | FFAR4HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13009610 | 0.70 | HTR1A (0.47) | HTR1AHRH3CARM1 | |
| SCHEMBL2888037 | 0.70 | FFAR4 (0.36) | FFAR4CNR1CNR2FFAR1TRPV6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7700653-B2 | Halogen-substituted aminodicarboxylic acid derivatives | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-04-20 | — | — | US | disclosed |
| US-7067694-B2 | Halogen-substituted amino dicarboxylic acid derivatives as medicaments for treating cardiovascular diseases | BAYER AKTIENGESELLSCHAFT (DE) | 2006-06-27 | — | — | US | disclosed |
| US-20060111444-A1 | Novel halogen-substituted aminodicarboxylic acid derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2006-05-25 | — | — | US | disclosed |
| EP-1368303-B1 | HALOGEN-SUBSTITUTED AMINO DICARBOXYLIC ACID DERIVATIVES AS MEDICAMENTS FOR TREATING CARDIOVASCULAR DISEASES | BAYER HEALTHCARE AG (DE) | 2004-12-15 | — | — | EP | disclosed |
| US-20040092593-A1 | Halogen-substituted amino dicarboxylic acid derivatives as medicaments for treating cardiovascular diseases | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2004-05-13 | — | — | US | disclosed |
| EP-1368303-A1 | HALOGEN-SUBSTITUTED AMINO DICARBOXYLIC ACID DERIVATIVES AS MEDICAMENTS FOR TREATING CARDIOVASCULAR DISEASES | Bayer Aktiengesellschaft (DE) | 2003-12-10 | — | — | EP | disclosed |
| WO-2002070460-A1 | HALOGEN-SUBSTITUTED AMINO DICARBOXYLIC ACID DERIVATIVES AS MEDICAMENTS FOR TREATING CARDIOVASCULAR DISEASES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092593-A1 | Halogen-substituted amino dicarboxylic acid derivatives as medicaments for treating cardiovascular diseases | BCAT2, DDC, AADAT | FFAR4 321/4885HTR1A 2645/4885SLC6A2 563/4885 |
| US-20060111444-A1 | Novel halogen-substituted aminodicarboxylic acid derivatives | FABP3, PPARD, FABP1 | FFAR4 45/4885HTR1A 3781/4885SLC6A2 3076/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.