Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | CXCR5 | P32302 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HRH1 | P35367 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28860430 | 0.76 | HTR2A (0.39) | TRPM8LMNAHDAC9CXCR5POLB | |
| SCHEMBL26656365 | 0.75 | TRPM8 (0.37) | TRPM8LMNASIGMAR1HDAC9POLB | |
| SCHEMBL3520901 | 0.75 | POLB (0.47) | TRPM8LMNAHTTHDAC9POLB | |
| SCHEMBL11495165 | 0.75 | ALOX15 (0.41) | LMNAHTTSMN1; SMN2 | |
| SCHEMBL10934019 | 0.73 | LMNA (0.49) | TRPM8LMNAHTTPOLBL3MBTL1 | |
| SCHEMBL4383885 | 0.72 | PPARA (0.43) | TRPM8LMNACXCR5POLBL3MBTL1 | |
| SCHEMBL2023897 | 0.72 | MAOA (0.42) | LMNASIGMAR1HTR2ACYP2D6TSHR | |
| Acetic Acid SCHEMBL28604975 | 0.71 | LMNA (0.42) | TRPM8LMNAPOLBL3MBTL1PKM | |
| SCHEMBL444321 | 0.71 | CYP2D6 (0.36) | TRPM8LMNASIGMAR1POLBL3MBTL1 | |
| SCHEMBL3380544 | 0.71 | PPARA (0.44) | LMNACYP2D6TSHRCYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104884453-B | Anthelmintic compounds and compositions and methods of using the same | 梅里亚股份有限公司 | 2018-06-22 | — | — | CN | disclosed |