SCHEMBL28860671

SCHEMBL28860671

CCCCc1c(C(=O)O)c(O)cc2ccccc12

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC37A4 O43826 1/20 0.51
KDM4E B2RXH2 2/20 0.47
ALDH1A1 P00352 2/20 0.47
HPGD P15428 2/20 0.47
HSD17B10 Q99714 2/20 0.47
MEN1 O00255 1/20 0.47
CYP1A2 P05177 1/20 0.47
GLA P06280 1/20 0.47
CYP2C19 P33261 1/20 0.47
KMT2A Q03164 1/20 0.47
NCEH1 Q6PIU2 1/20 0.46
POLB P06746 1/20 0.46
GPR35 Q9HC97 1/20 0.46
ME2 P23368 1/20 0.45
ME1 P48163 1/20 0.45
ME3 Q16798 1/20 0.45
BID P55957 3/20 0.43
MCL1 Q07820 3/20 0.43
BCL2L1 Q07817 2/20 0.43
BAK1 Q16611 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7107682 0.94 KAT8 (0.51) SLC37A4KDM4EALDH1A1HPGDHSD17B10
SCHEMBL10684176 0.94 KAT8 (0.51) SLC37A4KDM4EALDH1A1HPGDHSD17B10
SCHEMBL21569596 0.89 NCEH1 (0.46) SLC37A4KDM4EALDH1A1HPGDHSD17B10
SCHEMBL28330445 0.82 MAPT (0.47) KDM4EALDH1A1HPGDHSD17B10MEN1
SCHEMBL29379734 0.82 GPR35 (0.61) KDM4EALDH1A1HPGDHSD17B10MEN1
SCHEMBL30689889 0.82 HPGD (0.50) KDM4EALDH1A1HPGDHSD17B10CYP1A2
SCHEMBL3619455 0.82 GPR35 (0.61) KDM4EALDH1A1HPGDHSD17B10MEN1
SCHEMBL10976271 0.82 HPGD (0.50) KDM4EALDH1A1HPGDHSD17B10CYP1A2
SCHEMBL6545326 0.80 HPGD (0.47) KDM4EALDH1A1HPGDHSD17B10NCEH1
SCHEMBL11024895 0.80 NCEH1 (0.45) KDM4EALDH1A1HPGDHSD17B10CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105658704-B Polymer composite, method of manufacture and use 伊斯曼柯达公司 2018-06-29 CN disclosed