Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Cyclohexylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 2/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclohexylamine SCHEMBL3501943 | 0.97 | ALDH1A1 (0.41) | ALDH1A1CA1CA2EPHX1MMP8 | |
| Cyclohexylamine SCHEMBL27744924 | 0.97 | ALDH1A1 (0.41) | ALDH1A1CA1CA2EPHX1MMP8 | |
| Cyclohexylamine SCHEMBL9792266 | 0.92 | ALDH1A1 (0.38) | ALDH1A1CA1CA2EPHX1MMP8 | |
| Cyclohexylamine SCHEMBL7357483 | 0.92 | CA1 (0.42) | ALDH1A1CA1CA2EPHX1MMP8 | |
| Cyclohexylamine SCHEMBL27711124 | 0.86 | CA1 (0.42) | ALDH1A1CA1CA2EPHX1MMP8 | |
| Cyclooctanamine SCHEMBL521739 | 0.86 | MMP8 (0.42) | ALDH1A1CA1CA2EPHX1MMP8 | |
| SCHEMBL520280 | 0.86 | MMP8 (0.42) | ALDH1A1CA1CA2EPHX1MMP8 | |
| Cyclohexylamine SCHEMBL27416385 | 0.86 | MMP8 (0.42) | ALDH1A1CA1CA2EPHX1MMP8 | |
| Sulfuric Acid SCHEMBL28248625 | 0.85 | — | — | |
| Cyclopentanamine SCHEMBL19198718 | 0.84 | ALDH1A1 (0.33) | ALDH1A1CA1CA2EPHX1MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108238995-A | The process units of sweetener Cyclohexylamino sodium sulphate | 成都波洛克科技有限公司 | 2018-07-03 | — | — | CN | claimed |
| CN-108238995-A | The process units of sweetener Cyclohexylamino sodium sulphate | 成都波洛克科技有限公司 | 2018-07-03 | — | — | CN | disclosed |
| CN-108238995-A | The process units of sweetener Cyclohexylamino sodium sulphate | 成都波洛克科技有限公司 | 2018-07-03 | — | — | CN | disclosed |
| CN-108238995-A | The process units of sweetener Cyclohexylamino sodium sulphate | 成都波洛克科技有限公司 | 2018-07-03 | — | — | CN | disclosed |