Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Cyclohexylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclohexylamine SCHEMBL27744924 | 1.00 | ALDH1A1 (0.41) | ALDH1A1CA1CA2EPHX1MMP1 | |
| Cyclohexylamine SCHEMBL28860745 | 0.97 | ALDH1A1 (0.39) | ALDH1A1CA1CA2EPHX1MMP1 | |
| Cyclohexylamine SCHEMBL9792266 | 0.95 | ALDH1A1 (0.38) | ALDH1A1CA1CA2EPHX1MMP1 | |
| Cyclohexylamine SCHEMBL27711124 | 0.89 | CA1 (0.42) | ALDH1A1CA1CA2EPHX1MMP1 | |
| Cyclooctanamine SCHEMBL521739 | 0.89 | MMP8 (0.42) | ALDH1A1CA1CA2EPHX1MMP1 | |
| Cyclohexylamine SCHEMBL27416385 | 0.89 | MMP8 (0.42) | ALDH1A1CA1CA2EPHX1MMP1 | |
| Cyclohexylamine SCHEMBL7357483 | 0.89 | CA1 (0.42) | ALDH1A1CA1CA2EPHX1MMP1 | |
| SCHEMBL520280 | 0.89 | MMP8 (0.42) | ALDH1A1CA1CA2EPHX1MMP1 | |
| Sulfuric Acid SCHEMBL28248625 | 0.87 | — | — | |
| Cyclopentanamine SCHEMBL19198718 | 0.87 | ALDH1A1 (0.33) | ALDH1A1CA1CA2EPHX1MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116650425-A | Use of sugar ester compounds or salts thereof in cryoprotection and freeze-drying protection | 晟迪生物医药(苏州)有限公司 | 2023-08-29 | — | — | CN | disclosed |
| CN-108570021-B | Vulcanization accelerator CBS and continuous production method thereof | 科迈化工股份有限公司 | 2022-08-16 | — | — | CN | disclosed |
| EP-2614733-B1 | Glove | SHOWA GLOVE CO (JP) | 2018-11-14 | — | — | EP | disclosed |
| CN-108586383-A | A kind of continuous production method of accelerator D CBS | 科迈化工股份有限公司 | 2018-09-28 | — | — | CN | disclosed |
| CN-108570021-A | A kind of aniline fluid bed and its continuous production method | 科迈化工股份有限公司 | 2018-09-25 | — | — | CN | disclosed |
| US-20160369237-A1 | METHODS TO ACCELERATE THE ISOLATION OF NOVEL CELL STRAINS FROM PLURIPOTENT STEM CELLS AND CELLS OBTAINED THEREBY | ADVANCED CELL TECH INC (US) | 2016-12-22 | — | — | US | disclosed |
| US-20130180028-A1 | GLOVE | SHOWA GLOVE CO. (JP) | 2013-07-18 | — | — | US | disclosed |
| EP-2614733-A2 | Glove | SHOWA GLOVE Co. (JP) | 2013-07-17 | — | — | EP | disclosed |
| CN-101245019-B | Novel technique for synthesizing quaternary ammonium salt | QIU JIANXING | 2011-04-20 | — | — | CN | disclosed |
| US-20100184033-A1 | METHODS TO ACCELERATE THE ISOLATION OF NOVEL CELL STRAINS FROM PLURIPOTENT STEM CELLS AND CELLS OBTAINED THEREBY | Lineage Cell Therapeutics, Inc. | 2010-07-22 | — | — | US | disclosed |
| CN-101245019-A | Novel technique for synthesizing quaternary ammonium salt | QIU JIANXING (CN) | 2008-08-20 | — | — | CN | disclosed |
| EP-1903873-A2 | HERPES VIRUS-BASED COMPOSITIONS AND METHODS OF USE IN THE PRENATAL AND PERINATAL PERIODS | THE UNIVERSITY OF ROCHESTER (US) | 2008-04-02 | — | — | EP | disclosed |
| US-20080070303-A1 | Using myocardial and/or muscle progenitor cells as modeling tool in tissue engineering; regenerative medicine and organ replacement | ADVANCED CELL TECHNOLOGY | 2008-03-20 | — | — | US | disclosed |
| WO-2007062198-A1 | METHODS TO ACCELERATE THE ISOLATION OF NOVEL CELL STRAINS FROM PLURIPOTENT STEM CELLS AND CELLS OBTAINED THEREBY | ADVANCED CELL TECHNOLOGY, INC. (US) | 2007-05-31 | — | — | WO | disclosed |
| WO-2006135602-A2 | HERPES VIRUS-BASED COMPOSITIONS AND METHODS OF USE IN THE PRENATAL AND PERINATAL PERIODS | UNIVERSITY OF ROCHESTER (US) | 2006-12-21 | — | — | WO | disclosed |
| US-4753736-A | USING AQUEOUS SOLUTION OF CITRATE SALT OF VOLATILE AMINE | BETZ LABORATORIES, INC. (US) | 1988-06-28 | — | — | US | disclosed |
| US-4663421-A | Polyarylate having amide terminal groups | GENERAL ELECTRIC COMPANY (US) | 1987-05-05 | — | — | US | disclosed |
| US-4557856-A | Electrically conductive composition for electro-responsive recording materials | MITA INDUSTRIAL CO., LTD. (JP) | 1985-12-10 | — | — | US | disclosed |
| US-4506064-A | HEAT RESISTANT MOLDING MATERIALS | GENERAL ELECTRIC COMPANY (US) | 1985-03-19 | — | — | US | disclosed |
| US-4206088-A | ACID /ADDITION SALT OF ORGANONITROGEN BASE ABOSRBED ON SOLID INORGANIC ACID | MITA INDUSTRIAL COMPANY LIMITED (JP) | 1980-06-03 | — | — | US | disclosed |