Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 1/20 | 0.51 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | TSPO | P30536 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8842551 | 0.80 | HTT (0.51) | MEN1KMT2AGAASMN1; SMN2TSHR | |
| SCHEMBL27639739 | 0.77 | PARP10 (0.53) | CTNNB1KMT2ASMN1; SMN2TSHRPARP10 | |
| SCHEMBL7642520 | 0.76 | HSD17B10 (0.46) | MEN1KMT2AGAASMN1; SMN2TSHR | |
| SCHEMBL28016848 | 0.76 | GAA (0.40) | L3MBTL1GAA | |
| SCHEMBL3826083 | 0.76 | ADRA2C (0.71) | CTNNB1ADRA2CMAPK1MEN1KMT2A | |
| SCHEMBL29757946 | 0.76 | ADRA2C (0.71) | CTNNB1ADRA2CMAPK1MEN1KMT2A | |
| SCHEMBL28030648 | 0.74 | MAPT (0.48) | MAPK1MEN1KMT2AGAAPKM | |
| SCHEMBL27661025 | 0.72 | MAPT (0.46) | MAPK1MEN1KMT2AGAAPKM | |
| SCHEMBL9332916 | 0.72 | TSHR (0.42) | L3MBTL1GAASMN1; SMN2TSHRPOLB | |
| SCHEMBL27455333 | 0.71 | BCAT2 (0.47) | MEN1KMT2AL3MBTL1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108369222-A | Opioid receptor modulators and uses thereof | 明尼苏达大学董事会 | 2018-08-03 | — | — | CN | disclosed |